A New Zn (II) Coordination Compound: Anti-Inflammatory Activity in Ankylosing Spondylitis

被引：0

作者：

Cheng, Zheng-Jie ^{[1
]}

Ma, Xin ^{[1
]}

机构：

[1] Fudan Univ, Affiliated Huashan Hosp, Dept Orthoped, Shanghai, Peoples R China

来源：

LATIN AMERICAN JOURNAL OF PHARMACY | 2017年 / 36卷 / 01期

关键词：

Metal-organic; Coordination framework; Anti-inflammatory; DNA; RECOGNITION; PREVALENCE; COMPLEXES;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A new three-dimensional (3-D) Zn-based metal-organic framework with the formula of [Zn-2(L)(bpy)](CI) (1, H3L = 2,6-dihydroxypyridine-4-carboxylate, bpy = 4,4'-bipyridine), has been synthesized under hydrothermal condition. X-Ray diffraction analyse reveals that compound 1 exhibits the unique 3-D two-fold interpenetrated coordination framework with 3,4-connected fsx-3,4-C2 network topology, in which the L ligand adopts the mu(3)-bridging fashion. In addition, the experimental results of anti-inflammatory activity showed that compared with organic ligands H3L and bpy, the title compound 1 exerted rather potent activity.

引用

页码：196 / 199

页数：4

共 12 条

[1]

[Anonymous], 1997, SHELXL 97 PROGRAM CR

[2] Work status and productivity costs due to ankylosing spondylitis:: comparison of three European countries [J].

Boonen, A ;

van der Heijde, D ;

Landewé, R ;

Spoorenberg, A ;

Schouten, H ;

Rutten-van Mölken, M ;

Guillemin, F ;

Dougados, M ;

Mielants, H ;

de Vlam, K ;

van der Tempel, H ;

van der Linden, S .

ANNALS OF THE RHEUMATIC DISEASES, 2002, 61 (05) :429-437

[3]

Braun J, 1998, ARTHRITIS RHEUM-US, V41, P58, DOI 10.1002/1529-0131(199801)41:1<58::AID-ART8>3.3.CO

[4]

2-7

[5] Ternary copper complexes for photocleavage of DNA by red light: Direct evidence for sulfur-to-copper charge transfer and D-D band involvement [J].

Dhar, S ;

Senapati, D ;

Das, PK ;

Chattopadhyay, P ;

Nethaji, M ;

Chakravarty, AR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (40) :12118-12124

[6] Supramolecular DNA recognition [J].

Hannon, Michael J. .

CHEMICAL SOCIETY REVIEWS, 2007, 36 (02) :280-295

[7] A versatile mismatch recognition agent: Specific cleavage of a plasmid DNA at a single base mispair [J].

Jackson, BA ;

Alekseyev, VY ;

Barton, JK .

BIOCHEMISTRY, 1999, 38 (15) :4655-4662

[8]

Lawrence RC, 1998, ARTHRITIS RHEUM-US, V41, P778, DOI 10.1002/1529-0131(199805)41:5<778::AID-ART4>3.0.CO

[9]

2-V

[10]

Linden S.M.Van der, 1998, J RHEUMATOL, V15, P375

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