Anthracycline Chemotherapy-Induced Cardiotoxicity in Breast Cancer Survivors: A Systematic Review

被引:8
作者
Lin, Katherine Jinghua [1 ]
Lengacher, Cecile A. [2 ]
机构
[1] Pasco Hernando State Coll, Wesley Chapel, FL 33543 USA
[2] Univ S Florida, Coll Nursing, Tampa, FL USA
关键词
anthracycline; cardiotoxicity; breast cancer; survivors; HEART-FAILURE; ADJUVANT CHEMOTHERAPY; CARDIAC DYSFUNCTION; SYSTOLIC FUNCTION; FOLLOW-UP; TRASTUZUMAB; DOXORUBICIN; EPIRUBICIN; RISK; ECHOCARDIOGRAPHY;
D O I
10.1188/19.ONF.E145-E158
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
PROBLEM IDENTIFICATION: This review identifies specific cardiotoxicity related to anthracycline chemotherapy, specific risk factors related to increased anthracycline chemotherapy-induced cardiotoxicity, and underlying mechanisms of action of anthracycline chemotherapy-induced cardiotoxicity. LITERATURE SEARCH: PubMed (R) CINAHL (R) Embase (R), and Web of Science were searched in May 2018 using keywords related to heart diseases, anthracycline chemotherapy, and breast cancer. DATA EVALUATION: Data were extracted, and study quality was assessed according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. SYNTHESIS: 1.117 articles were identified through the literature search. After a review of the abstracts and articles, 15 clinical studies were identified for the final analysis by using exclusion and inclusion criteria. IMPLICATIONS FOR PRACTICE: Nurses should recognize the critical elements for prevention and early detection of anthracycline chemotherapy-induced cardiotoxicity.
引用
收藏
页码:E145 / E158
页数:14
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