Definitions for warning signs and signs of severe dengue according to the WHO 2009 classification: Systematic review of literature

被引:39
作者
Morra, Mostafa Ebraheem [1 ]
Altibi, Ahmed M. A. [2 ]
Iqtadar, Somia [3 ]
Le Huu Nhat Minh [4 ]
Elawady, Sameh Samir [5 ]
Hallab, Asma [6 ]
Elshafay, Abdelrahman [1 ]
Omer, Omer Abedlbagi [7 ]
Iraqi, Ahmed [8 ]
Adhikari, Purushottam [9 ]
Labib, Jonair Hussein [10 ]
Elhusseiny, Khaled Mosaad [1 ]
Elgebaly, Ahmed [1 ]
Yacoub, Sophie [11 ,12 ]
Le Thi Minh Huong [13 ]
Hirayama, Kenji [14 ]
Nguyen Tien Huy [15 ,16 ,17 ]
机构
[1] Al Azhar Univ, Fac Med, Cairo, Egypt
[2] Univ Jordan, Fac Med, Amman, Jordan
[3] King Edward Med Univ, Fac Med, Lahore, Pakistan
[4] Univ Med & Pharm Ho Chi Minh City, Ho Chi Minh City, Vietnam
[5] Tanta Univ, Fac Med, Tanta, Egypt
[6] UPMC, Sorbonne Univ, Paris 06, France
[7] Univ Gezira, Fac Med, Wad Madani, Sudan
[8] Cairo Univ Hosp, Giza, Egypt
[9] Gandaki Med Coll, Pokhara, Nepal
[10] Ain Shams Univ, Dept Pediat, Fac Med, Cairo, Egypt
[11] Univ Oxford, Clin Res Unit, Ho Chi Minh City, Vietnam
[12] Imperial Coll London, Med, London, England
[13] Tien Giang Hosp, Dept Emergency Crit Care Med & Med Toxicol, My Tho, Vietnam
[14] Nagasaki Univ, Inst Trop Med NEKKEN, Leading Grad Sch Program, Grad Sch Biomed Sci,Dept Immunogenet, Nagasaki, Japan
[15] Ton Duc Thang Univ, Evidence Based Med Res Grp, Ho Chi Minh City, Vietnam
[16] Ton Duc Thang Univ, Fac Sci Appl, Ho Chi Minh City, Vietnam
[17] Nagasaki Univ, Inst Trop Med NEKKEN, Grad Sch Biomed Sci, Dept Clin Produ Dev,Leading Grad Sch Program, Nagasaki, Japan
关键词
classification; dengue; severe signs; warning signs; RISK-FACTORS; CHILDREN; FEVER; APPLICABILITY; INFECTION; ADULTS;
D O I
10.1002/rmv.1979
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Since warning signs and signs of severe dengue are defined differently between studies, we conducted a systematic review on how researchers defined these signs. We conducted an electronic search in Scopus to identify relevant articles, using key words including dengue, warning signs, severe dengue, and classification. A total of 491 articles were identified through this search strategy and were subsequently screened by 2 independent reviewers for definitions of any of the warning or severe signs in the 2009 WHO dengue classification. We included all original articles published in English after 2009, classifying dengue by the 2009 WHO classification or providing the additional definition or criterion of warning signs and severity (besides the information of 2009 WHO). Analysis of the extracted data from 44 articles showed wide variations among definitions and cutoff values used by physicians to classify patients diagnosed with dengue infection. The establishment of clear definitions for warning signs and severity is essential to prevent unnecessary hospitalization and harmonizing the interpretation and comparability of epidemiological studies dedicated to dengue infection.
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页数:11
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