LCPUFAs as Conditionally Essential Nutrients for Very Low Birth Weight and Low Birth Weight Infants: Metabolic, Functional, and Clinical Outcomes-How Much is Enough?

被引：14
作者：
Makrides, Maria [1 ,2 ]
Uauy, Ricardo [3 ,4 ]
机构：
[1] South Australian Hlth & Med Res Inst, Adelaide, SA 5000, Australia
[2] Univ Adelaide, Womens & Childrens Hlth Res Inst, Adelaide, SA 5006, Australia
[3] Catholic Univ Chile, Sch Med, Dept Pediat, Div Neonatol, Santiago, Chile
[4] Univ Chile, INTA, Inst Nutr, Santiago, Chile
来源：
CLINICS IN PERINATOLOGY | 2014年 / 41卷 / 02期
关键词：
Preterm; Low birth weight infants; Very low birth weight infants; LCPUFA; Randomized controlled trials; Development; FATTY-ACID SUPPLEMENTATION; DOSE DOCOSAHEXAENOIC ACID; PRETERM INFANTS; VISUAL-ACUITY; DOUBLE-BLIND; GROWTH; OIL; NEURODEVELOPMENT; DEFICIENCY; TRIAL;
D O I：
10.1016/j.clp.2014.02.012
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Preterm infants are denied the rapid accumulation of docosahexaenoic acid (DHA) occurring during the third trimester in utero. The potential benefit of long-chain polyunsaturated fatty acids (LCPUFAs) has generated interest over the last 3 decades. Early intervention trials assessed the effects of supplementing infant formulas lacking DHA with concentrations equivalent to LCPUFA in milk of women from Westernized societies, leading to the inclusion of LCPUFA by the year 2000. Recently attention has been on determining the optimal dose of DHA and on whether there is in advantage in matching the higher doses of late pregnancy.
引用
收藏
页码：451 / 461
页数：11
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