Age-related changes in ultrastructure of mitochondria. Effect of SkQ1

被引：6

作者：

Bakeeva, L. E. ^{[1
]}

机构：

[1] Moscow MV Lomonosov State Univ, Belozersky Inst Physicochem Biol, Moscow 119991, Russia

来源：

BIOCHEMISTRY-MOSCOW | 2015年 / 80卷 / 12期

关键词：

aging; mitochondrial ultrastructure; age-related changes; TARGETED PLASTOQUINONE DERIVATIVES; SKELETAL-MUSCLE; INTERRUPT EXECUTION; SENESCENCE; FLIGHT; TOOLS;

D O I：

10.1134/S0006297915120068

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

For many years, investigators have attempted to identify unique ultrastructural conditions of mitochondria related to aging. However, this did not result in definitive results. At present, this issue has again become of topical interest due to development of the mitochondrial theory of aging and of engineering of a novel antioxidant class known as mitochondria-targeted antioxidants. The review briefly discusses experimental results that, from our perspective, allow the most objective understanding regarding age-related changes in mitochondrial ultrastructure.

引用

页码：1582 / 1588

页数：7

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