How size evaluation of lymph node is protocol dependent in MRI when using ultrasmall superparamagnetic iron oxide nanoparticles

被引：9
作者：
Gharehaghaji, Nahideh [1 ,2 ]
Oghabian, Mohammad Ali [1 ,2 ]
Sarkar, Saeed [1 ,2 ]
Darki, Fahimeh [1 ]
Beitollahi, Ali [3 ]
机构：
[1] Univ Tehran Med Sci, Res Ctr Sci & Technol Med, Emam Hosp, Tehran, Iran
[2] Univ Tehran Med Sci, Dept Med Phys & Biomed Engn, Tehran, Iran
[3] IUST, Nanomat Grp, Dept Met Eng, Tehran, Iran
来源：
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2009年 / 321卷 / 10期
关键词：
Iron oxide nanoparticles; USPIO; Magnetic resonance lymphography; Susceptibility artifact; Rat axillary lymph node; INITIAL CLINICAL-EXPERIENCE; SUSCEPTIBILITY ARTIFACTS; METASTASES; CANCER; LYMPHOGRAPHY; CARCINOMA; PARTICLES; HEAD;
D O I：
10.1016/j.jmmm.2009.02.086
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
In this study, the volume of susceptibility artifact was evaluated in T1 and T2-weighted spin echo (SE) and gradient echo (GRE) images at various parameters using registration and subtraction methods. In order to state an important misinterpretation problem in lymphography, it was demonstrated that a lymph node size may be enlarged approximately 10 times when a T2*-weighted GRE protocol is used. To overcome this problem a technical consideration using multisequence (GRE and SE) paradigm was suggested to ensure both lymph node detection and metastasis identification in lymphatic system. The paradigm was also extended by post-processing manipulation of the SE images using a registration and subtraction approach for detection of lymphatic lesions. (C) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码：1563 / 1565
页数：3
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