Uric acid and cardiovascular risk

被引：142
作者：
Alderman, MH [1 ]
机构：
[1] Albert Einstein Coll Med, Bronx, NY 10461 USA
来源：
CURRENT OPINION IN PHARMACOLOGY | 2002年 / 2卷 / 02期
关键词：
D O I：
10.1016/S1471-4892(02)00143-1
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Uric acid has long been associated with cardiovascular disease. Most epidemiological evidence suggests a significant, graded, independent and specific association between the level of serum uric acid and cardiovascular morbidity and mortality. This is particularly robust among persons at high cardiovascular risk, including those with hypertension, diabetes and congestive heart failure. Although several potential mechanisms have been identified to explain this association, as yet there is no evidence that uric acid bears a causal or reversible relationship to vascular disease.
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页码：126 / 130
页数：5
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