Gastrointestinal involvement at the onset of granulomatosis with polyangiitis: A case report

被引：6

作者：

Yoshikawa, Ayaka ^{[1
]}

Yoshida, Shuzo ^{[1
]}

Takeuchi, Tohru ^{[1
]}

Fujiki, Yohei ^{[1
]}

Makino, Shigeki ^{[1
]}

Hanafusa, Toshiaki ^{[1
]}

机构：

[1] Osaka Med Coll, Dept Internal Med 1, 2-7 Daigakumachi, Takatsuki, Osaka 5698686, Japan

来源：

MODERN RHEUMATOLOGY | 2017年 / 27卷 / 01期

关键词：

Granulomatosis with polyangiitis; Oral intestinal symptoms; Azathioprine; PR3-ANCA; Primary manifestation; SEVERE INTESTINAL INVOLVEMENT; WEGENERS-GRANULOMATOSIS; INITIAL PRESENTATION; COLITIS; PERFORATION; DISEASE;

D O I：

10.3109/14397595.2014.954742

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 30-year-old man had developed fever, bloody stools, and oral aphtha. Proteinase 3-antineutrophil cytoplasmic antibody level was 31 EU. Lower intestinal endoscopy revealed edematous mucosa with hemorrhage in the transverse colon. Biopsies of oral aphtha showed necrotizing angiitis with granuloma. Based on these findings, he was diagnosed with granulomatosis with polyangiitis (GPA). Digestive symptoms were remitted by treatment with prednisolone and azathioprine. GPA with digestive symptoms as the initial development is rare.

引用

页码：162 / 164

页数：3

共 24 条

[1]

Akca Tamer, 2005, Ulus Travma Acil Cerrahi Derg, V11, P348

[2] Severe intestinal involvement in Wegener's granulomatosis [J].

Chow, FYF ;

Hooke, D ;

Kerr, PG .

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2003, 18 (06) :749-750

[3]

Corne P, 1997, GASTROEN CLIN BIOL, V21, P163

[4]

David MS, 2011, INT J COLORECTAL DIS, V26, P259

[5]

Deniz K, 2007, J GASTROINTEST LIVER, V16, P329

[6] Recent advances in understanding ulcerative colitis [J].

Di Sabatino, Antonio ;

Biancheri, Paolo ;

Rovedatti, Laura ;

MacDonald, Thomas Thornton ;

Corazza, Gino Roberto .

INTERNAL AND EMERGENCY MEDICINE, 2012, 7 (02) :103-111

[7] INTESTINAL PERFORATION IN WEGENERS GRANULOMATOSIS [J].

GERAGHTY, J ;

MACKAY, IR ;

SMITH, DC .

GUT, 1986, 27 (04) :450-451

[8] SEVERE INTESTINAL INVOLVEMENT IN WEGENER GRANULOMATOSIS [J].

HAWORTH, SJ ;

PUSEY, CD .

GUT, 1984, 25 (11) :1296-1300

[9]

Hisabe T, 2013, J GASTROEMTEROL

[10] Colonoscopic findings in intestinal Behcet's disease [J].

Lee, CR ;

Kim, WH ;

Cho, YS ;

Kim, MH ;

Kim, JH ;

Park, IS ;

Bang, D .

INFLAMMATORY BOWEL DISEASES, 2001, 7 (03) :243-249

← 1 2 3 →