Shaping the actin cytoskeleton using microtubule tips

被引：67
|
作者：
Basu, Roshni [1 ]
Chang, Fred [1 ]
机构：
[1] Columbia Univ Coll Phys & Surg, Dept Microbiol, New York, NY 10032 USA
来源：
CURRENT OPINION IN CELL BIOLOGY | 2007年 / 19卷 / 01期
关键词：
D O I：
10.1016/j.ceb.2006.12.012
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The microtubule cytoskeleton serves as a primary spatial regulator of cell shape. As part of their function, microtubules appear to activate or inhibit the actin cytoskeleton at specific locations at the cell cortex for cell polarization, cell migration and cytokinesis. Recent studies reveal molecular insights into these processes. Regulators of the actin cytoskeleton, such as activators of formin and Rho GTPases, are transported to specific sites on the cortex by riding on the plus ends of microtubules.
引用
收藏
页码：88 / 94
页数：7
相关论文
共 50 条
  • [1] Actin and microtubule cytoskeleton interactions
    Petrasek, Jan
    Schwarzerova, Katerina
    CURRENT OPINION IN PLANT BIOLOGY, 2009, 12 (06) : 728 - 734
  • [2] Microtubule tips redirect actin assembly
    Bretscher, A
    DEVELOPMENTAL CELL, 2005, 8 (04) : 458 - 459
  • [3] Coordination of microtubule acetylation and the actin cytoskeleton by formins
    Jaime Fernández-Barrera
    Miguel A. Alonso
    Cellular and Molecular Life Sciences, 2018, 75 : 3181 - 3191
  • [4] Coordination of microtubule acetylation and the actin cytoskeleton by formins
    Fernandez-Barrera, Jaime
    Alonso, Miguel A.
    CELLULAR AND MOLECULAR LIFE SCIENCES, 2018, 75 (17) : 3181 - 3191
  • [5] In vitro analysis of microtubule and actin cytoskeleton interactions
    Mandato, CA
    Zandy, A
    Weber, KL
    Bement, WM
    MOLECULAR BIOLOGY OF THE CELL, 1998, 9 : 39A - 39A
  • [6] Merlin differentially associates with the microtubule and actin cytoskeleton
    Xu, HM
    Gutmann, DH
    JOURNAL OF NEUROSCIENCE RESEARCH, 1998, 51 (03) : 403 - 415
  • [7] Dynamic linkage of the keratin cytoskeleton to the actin and microtubule systems
    Windoffer, R
    Wöll, S
    Leube, RE
    MOLECULAR BIOLOGY OF THE CELL, 2004, 15 : 297A - 297A
  • [8] Probing the microtubule-actin cytoskeleton interface.
    Kaverina, IN
    Rottner, K
    Small, JV
    MOLECULAR BIOLOGY OF THE CELL, 1998, 9 : 257A - 257A
  • [9] Dynamic regulation of the microtubule and actin cytoskeleton in zebrafish epiboly
    Lee, Shyh-Jye
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2014, 452 (01) : 1 - 7
  • [10] Interdependence of the actin and the microtubule cytoskeleton during fungal growth
    Takeshita, Norio
    Manck, Raphael
    Gruen, Nathalie
    de Vega, Satur Herrero
    Fischer, Reinhard
    CURRENT OPINION IN MICROBIOLOGY, 2014, 20 : 34 - 41
12345