Microfluidic Studies of Polymer Adsorption in Flow

被引：3
作者：
Salari, Alinaghi [1 ]
Kumacheva, Eugenia [1 ,2 ,3 ]
机构：
[1] Univ Toronto, Dept Chem Engn, 200 Coll St, Toronto, ON M5S 3E5, Canada
[2] Univ Toronto, Dept Chem, 80 St George St, Toronto, ON M5S 3H6, Canada
[3] Univ Toronto, Inst Biomat & Biomed Engn, 164 Coll St, Toronto, ON M5S 3G9, Canada
来源：
MACROMOLECULAR CHEMISTRY AND PHYSICS | 2017年 / 218卷 / 02期
基金：
加拿大自然科学与工程研究理事会;
关键词：
biopolymers; flow field; microfluidics; polymer adsorption; shear rate; QUARTZ-CRYSTAL MICROBALANCE; AC ELECTROKINETICS; SURFACE; MINERALIZATION; IMMUNOSENSOR; FORCES;
D O I：
10.1002/macp.201600328
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Adsorption of polymer molecules under flow conditions governs a broad range of desired or undesired phenomena and has a broad range of applications. Microfluidic platforms integrated with analytical instrumentation offer the capability to study polymer adsorption in flow in a time- and labour-efficient manner. Precise control of the microchannel dimensions and flow parameters enables accurate control of shear forces imposed on polymer solutions and on the molecules deposited on the surface, along with high sensitivity, enhanced reliability, and low reagent consumption. This review highlights recent advances in theoretical and experimental microfluidic studies of polymer immobilization under flow conditions in three area, namely, biosensing, biofouling, and studies of thrombosis and hemostasis.
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页数：16
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