Effectiveness of estrogen in the prevention of intrauterine adhesions after hysteroscopic septal resection: A prospective, randomized study

被引：47

作者：

Roy, Kallol Kumar ^{[1
]}

Negi, Neha ^{[1
]}

Subbaiah, Murali ^{[1
]}

Kumar, Sunesh ^{[1
]}

Sharma, Jai Bhagwan ^{[1
]}

Singh, Neeta ^{[1
]}

机构：

[1] All India Inst Med Sci, Dept Obstet & Gynecol, New Delhi, India

来源：

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH | 2014年 / 40卷 / 04期

关键词：

adhesions; estrogen treatment; hysteroscopy; reproductive outcome; septal resection; METROPLASTY; INFERTILITY; MANAGEMENT; UTERUS; WOMEN;

D O I：

10.1111/jog.12297

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

AimThe aim of this prospective randomized study was to evaluate the efficacy of estrogen in preventing intrauterine adhesions following hysteroscopic septal resection and to investigate its effect on reproductive outcome. Materials and MethodsAfter hysteroscopic septal resection, 90 women received either estrogen or placebo (n=45 per group) for 30 days. A second-look hysteroscopy was performed after 2 months. All pregnancies occurring during the study period were recorded. ResultsAdhesions developed in three of 43 (6.9%) patients in the control group compared to none in the estrogen group. This difference was not statistically significant (P=0.24). Regarding reproductive outcome, the differences between the two groups were also not significant. ConclusionEstrogen treatment was not found to prevent intrauterine adhesions or improve reproductive outcome after hysteroscopic septal resection.

引用

页码：1085 / 1088

页数：4

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