Electrospun scaffolds for tissue engineering of vascular grafts

被引：588

作者：

Hasan, Anwarul ^{[1
,2
]}

Memic, Adnan ^{[3
]}

Annabi, Nasim ^{[1
,2
]}

Hossain, Monowar ^{[4
]}

Paul, Arghya ^{[1
,2
]}

Dokmeci, Mehmet R. ^{[1
,2
]}

Dehghani, Fariba ^{[5
]}

Khademhosseini, Ali ^{[1
,2
,6
,7
]}

机构：

[1] Harvard Univ, Sch Med, Brigham & Womens Hosp, Ctr Biomed Engn,Dept Med, Cambridge, MA 02139 USA

[2] MIT, Harvard Mit Div Hlth Sci & Technol, Cambridge, MA 02139 USA

[3] King Abdulaziz Univ, Ctr Nanotechnol, Jeddah 21589, Saudi Arabia

[4] Univ Adelaide, Lyell McEwin Hosp, Dept Med, Adelaide, SA 5112, Australia

[5] Univ Sydney, Sch Chem & Biomol Engn, Sydney, NSW 2006, Australia

[6] Harvard Univ, Wyss Inst Biol Inspired Engn, Boston, MA 02115 USA

[7] Tohoku Univ, WPI AIMR, Sendai, Miyagi 9808577, Japan

来源：

ACTA BIOMATERIALIA | 2014年 / 10卷 / 01期

基金：

英国医学研究理事会; 美国国家科学基金会; 加拿大自然科学与工程研究理事会; 美国国家卫生研究院;

关键词：

Electrospinning; Tubular scaffolds; Vascular grafts; Tissue engineering; Mechanical properties; SURFACE MODIFICATION; BLOOD-VESSEL; STEM-CELLS; PORE-SIZE; EXTRACELLULAR-MATRIX; POLYMER NANOFIBERS; FIBER DIAMETER; ADHESION; ACID); PROLIFERATION;

D O I：

10.1016/j.actbio.2013.08.022

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

There is a growing demand for off-the-shelf tissue engineered vascular grafts (TEVGs) for the replacement or bypass of damaged arteries in various cardiovascular diseases. Scaffolds from the decellularized tissue skeletons to biopolymers and biodegradable synthetic polymers have been used for fabricating TEVGs. However, several issues have not yet been resolved, which include the inability to mimic the mechanical properties of native tissues, and the ability for long-term patency and growth required for in vivo function. Electrospinning is a popular technique for the production of scaffolds that has the potential to address these issues. However, its application to human TEVGs has not yet been achieved. This review provides an overview of tubular scaffolds that have been prepared by electrospinning with potential for TEVG applications. (C) 2013 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

引用

页码：11 / 25

页数：15

共 112 条

[1] Use of electrospinning technique for biomedical applications [J].

Agarwal, Seema ;

Wendorff, Joachim H. ;

Greiner, Andreas .

POLYMER, 2008, 49 (26) :5603-5621

[2]

Annabi N, 2010, TISSUE ENG PART B-RE, V16, P371, DOI [10.1089/ten.teb.2009.0639, 10.1089/ten.TEB.2009.0639]

[3] Surface controlled biomimetic coating of polycaprolactone nanofiber meshes to be used as bone extracellular matrix analogues [J].

Araujo, J. V. ;

Martins, A. ;

Leonor, I. B. ;

Pinho, E. D. ;

Reis, R. L. ;

Neves, N. M. .

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 2008, 19 (10) :1261-1278

[4] Effect of fiber diameter on spreading, proliferation, and differentiation of osteoblastic cells on electrospun poly(lactic acid) substrates [J].

Badami, AS ;

Kreke, MR ;

Thompson, MS ;

Riffle, JS ;

Goldstein, AS .

BIOMATERIALS, 2006, 27 (04) :596-606

[5] Characterisation of electrospun polystyrene scaffolds for three-dimensional in vitro biological studies [J].

Baker, SC ;

Atkin, N ;

Gunning, PA ;

Granville, N ;

Wilson, K ;

Wilson, D ;

Southgate, J .

BIOMATERIALS, 2006, 27 (16) :3136-3146

[6] Nanofiber technology: Designing the next generation of tissue engineering scaffolds [J].

Barnes, Catherine P. ;

Sell, Scott A. ;

Boland, Eugene D. ;

Simpson, David G. ;

Bowlin, Gary L. .

ADVANCED DRUG DELIVERY REVIEWS, 2007, 59 (14) :1413-1433

[7] Electrospinning: A fascinating fiber fabrication technique [J].

Bhardwaj, Nandana ;

Kundu, Subhas C. .

BIOTECHNOLOGY ADVANCES, 2010, 28 (03) :325-347

[8] Utilizing acid pretreatment and electrospinning to improve biocompatibility of poly(glycolic acid) for tissue engineering [J].

Boland, ED ;

Telemeco, TA ;

Simpson, DG ;

Wnek, GE ;

Bowlin, GL .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2004, 71B (01) :144-152

[9] Electrospinning approaches toward scaffold engineering - A brief overview [J].

Boudriot, Ulrich ;

Dersch, Roland ;

Greiner, Andreas ;

Wendorff, Joachim H. .

ARTIFICIAL ORGANS, 2006, 30 (10) :785-792

[10] Substrates for cardiovascular tissue engineering [J].

Bouten, C. V. C. ;

Dankers, P. Y. W. ;

Driessen-Mol, A. ;

Pedron, S. ;

Brizard, A. M. A. ;

Baaijens, F. P. T. .

ADVANCED DRUG DELIVERY REVIEWS, 2011, 63 (4-5) :221-241

← 1 2 3 4 5 6 7 8 9 10 →