Classification of antimicrobial peptide using diversity measure with quadratic discriminant analysis

被引：23

作者：

Chen, Wei ^{[1
]}

Luo, Liaofu ^{[1
]}

机构：

[1] Inner Mongolia Univ, Lab Theoret Biophys, Sch Phys Sci & Technol, Hohhot 010021, Peoples R China

来源：

JOURNAL OF MICROBIOLOGICAL METHODS | 2009年 / 78卷 / 01期

基金：

中国国家自然科学基金;

关键词：

Antimicrobial peptides; Increment of diversity; Quadratic discrimination; Dipeptide composition; AMINO-ACID-COMPOSITION; PROTEIN STRUCTURAL CLASSES; DEFENSE PEPTIDES; PREDICTION; ANTIBIOTICS;

D O I：

10.1016/j.mimet.2009.03.013

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Accurate classification of antimicrobial peptides according to their biological activities will facilitate the design of novel antimicrobial agents and the discovery of new therapeutic targets. In this work, an excellent algorithm of Increment of Diversity with Quadratic Discriminant analysis (IDQD) was proposed to classify antimicrobial peptides with diverse biological activities. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：94 / 96

页数：3

共 34 条

[21] Ribosomally synthesized peptides with antimicrobial properties: biosynthesis, structure, function, and applications [J].

Papagianni, M .

BIOTECHNOLOGY ADVANCES, 2003, 21 (06) :465-499

[22] Antimicrobial peptides from amphibian skin: an expanding scenario - Commentary [J].

Rinaldi, AC .

CURRENT OPINION IN CHEMICAL BIOLOGY, 2002, 6 (06) :799-804

[23]

Scott MG, 2000, CRIT REV IMMUNOL, V20, P407

[24] Effects of probiotics on the gastrointestinal tract [J].

Snelling, AM .

CURRENT OPINION IN INFECTIOUS DISEASES, 2005, 18 (05) :420-426

[25] Antimicrobial peptides: New candidates in the fight against bacterial infections [J].

Toke, O .

BIOPOLYMERS, 2005, 80 (06) :717-735

[26] Host Defense peptides: Roles and applications [J].

Tossi, A .

CURRENT PROTEIN & PEPTIDE SCIENCE, 2005, 6 (01) :1-3

[27] APD2: the updated antimicrobial peptide database and its application in peptide design [J].

Wang, Guangshun ;

Li, Xia ;

Wang, Zhe .

NUCLEIC ACIDS RESEARCH, 2009, 37 :D933-D937

[28] Using stacked generalization to predict membrane protein types based on pseudo-amino acid composition [J].

Wang, Shuang-Quan ;

Yang, Jie ;

Chou, Kuo-Chen .

JOURNAL OF THEORETICAL BIOLOGY, 2006, 242 (04) :941-946

[29] Using pseudo amino acid composition to predict protein structural classes: Approached with complexity measure factor [J].

Xiao, X ;

Shao, SH ;

Huang, ZD ;

Chou, KC .

JOURNAL OF COMPUTATIONAL CHEMISTRY, 2006, 27 (04) :478-482

[30]

Xiao X, 2006, AMINO ACIDS, V30, P49, DOI 10.1007/s00726-005-0225-6

← 1 2 3 4 →