Antimicrobial peptides;
Increment of diversity;
Quadratic discrimination;
Dipeptide composition;
AMINO-ACID-COMPOSITION;
PROTEIN STRUCTURAL CLASSES;
DEFENSE PEPTIDES;
PREDICTION;
ANTIBIOTICS;
D O I:
10.1016/j.mimet.2009.03.013
中图分类号:
Q5 [生物化学];
学科分类号:
071010 ;
081704 ;
摘要:
Accurate classification of antimicrobial peptides according to their biological activities will facilitate the design of novel antimicrobial agents and the discovery of new therapeutic targets. In this work, an excellent algorithm of Increment of Diversity with Quadratic Discriminant analysis (IDQD) was proposed to classify antimicrobial peptides with diverse biological activities. (C) 2009 Elsevier B.V. All rights reserved.
机构:
Univ Cagliari, Cattedra Chim biol, Dipartimento Sci Med Intern, I-09042 Monserrato, CA, ItalyUniv Cagliari, Cattedra Chim biol, Dipartimento Sci Med Intern, I-09042 Monserrato, CA, Italy
机构:
Washington Univ, Sch Med, Dept Biochem & Mol Biophys, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Biochem & Mol Biophys, St Louis, MO 63110 USA
机构:
Univ Nebraska Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USAUniv Nebraska Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USA
Wang, Guangshun
Li, Xia
论文数: 0引用数: 0
h-index: 0
机构:
Univ Nebraska Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USAUniv Nebraska Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USA
Li, Xia
Wang, Zhe
论文数: 0引用数: 0
h-index: 0
机构:
Univ Nebraska Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USAUniv Nebraska Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USA
机构:
Univ Cagliari, Cattedra Chim biol, Dipartimento Sci Med Intern, I-09042 Monserrato, CA, ItalyUniv Cagliari, Cattedra Chim biol, Dipartimento Sci Med Intern, I-09042 Monserrato, CA, Italy
机构:
Washington Univ, Sch Med, Dept Biochem & Mol Biophys, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Biochem & Mol Biophys, St Louis, MO 63110 USA
机构:
Univ Nebraska Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USAUniv Nebraska Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USA
Wang, Guangshun
Li, Xia
论文数: 0引用数: 0
h-index: 0
机构:
Univ Nebraska Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USAUniv Nebraska Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USA
Li, Xia
Wang, Zhe
论文数: 0引用数: 0
h-index: 0
机构:
Univ Nebraska Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USAUniv Nebraska Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USA