Classification of antimicrobial peptide using diversity measure with quadratic discriminant analysis

被引：23

作者：

Chen, Wei ^{[1
]}

Luo, Liaofu ^{[1
]}

机构：

[1] Inner Mongolia Univ, Lab Theoret Biophys, Sch Phys Sci & Technol, Hohhot 010021, Peoples R China

来源：

JOURNAL OF MICROBIOLOGICAL METHODS | 2009年 / 78卷 / 01期

基金：

中国国家自然科学基金;

关键词：

Antimicrobial peptides; Increment of diversity; Quadratic discrimination; Dipeptide composition; AMINO-ACID-COMPOSITION; PROTEIN STRUCTURAL CLASSES; DEFENSE PEPTIDES; PREDICTION; ANTIBIOTICS;

D O I：

10.1016/j.mimet.2009.03.013

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Accurate classification of antimicrobial peptides according to their biological activities will facilitate the design of novel antimicrobial agents and the discovery of new therapeutic targets. In this work, an excellent algorithm of Increment of Diversity with Quadratic Discriminant analysis (IDQD) was proposed to classify antimicrobial peptides with diverse biological activities. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：94 / 96

页数：3

共 34 条

[1] Cationic antimicrobial peptides - Issues for potential clinical use [J].

Bradshaw, JP .

BIODRUGS, 2003, 17 (04) :233-240

[2] Using amphiphilic pseudo amino acid composition to predict enzyme subfamily classes [J].

Chou, KC .

BIOINFORMATICS, 2005, 21 (01) :10-19

[3] PREDICTION OF PROTEIN STRUCTURAL CLASSES [J].

CHOU, KC ;

ZHANG, CT .

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1995, 30 (04) :275-349

[4] Human antimicrobial peptides: Analysis and application [J].

Cole, AM ;

Ganz, T .

BIOTECHNIQUES, 2000, 29 (04) :822-+

[5] Use of tetrapeptide signals for protein secondary-structure prediction [J].

Feng, Yonge ;

Luo, Liaofu .

AMINO ACIDS, 2008, 35 (03) :607-614

[6]

García-Olmedo F, 1998, BIOPOLYMERS, V47, P479, DOI 10.1002/(SICI)1097-0282(1998)47:6<479::AID-BIP6>3.0.CO

[7]

2-K

[8]

GARTIA A, 1925, COMPT REND SOC BIOL, V93, P1040

[9] Application of residue distribution along the sequence for discriminating outer membrane proteins [J].

Gromiha, MM ;

Ahmad, S ;

Suwa, M .

COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2005, 29 (02) :135-142

[10]

Hancock R E, 2001, Lancet Infect Dis, V1, P156, DOI 10.1016/S1473-3099(01)00092-5

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