Successful Treatment of Severe Right-Sided Heart Failure Due to Postoperative Constrictive Pericarditis With Tolvaptan

被引：5

作者：

Kanaya, Mitsuhiro ^{[1
]}

Matsushita, Kenichi ^{[1
]}

Inami, Takumi ^{[1
]}

Yamasaki, Satoko ^{[1
]}

Mizumi, Saiko ^{[1
]}

Minamishima, Toshinori ^{[1
]}

Goda, Ayumi ^{[1
]}

Ueda, Akiko ^{[1
]}

Sakata, Konomi ^{[1
]}

Satoh, Toru ^{[1
]}

Yoshino, Hideaki ^{[1
]}

机构：

[1] Kyorin Univ, Sch Med, Div Cardiol, Dept Internal Med 2, Mitaka, Tokyo 1818611, Japan

来源：

AMERICAN JOURNAL OF THERAPEUTICS | 2016年 / 23卷 / 01期

关键词：

cardiorenal syndrome; V2-receptor antagonist; diuretics; vaptan; fluid balance; ANTAGONISM;

D O I：

10.1097/MJT.0000000000000146

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The prognosis of inoperative constrictive pericarditis is poor due to subsequent severe right-sided heart failure that is refractory to conventional medical treatment. This case report describes the long-term treatment with tolvaptan, a new selective vasopression V2-receptor antagonist, was remarkably effective for inoperative constrictive pericarditis. Despite that tolvaptan was approved for the treatment of hyponatremia in Europe and the United States, the indications and treatment duration of it are not yet well established clinically. We propose that tolvaptan could offer an alternative option for the treatment of medically refractory severe right-sided heart failure such as constrictive pericarditis.

引用

页码：E264 / E267

页数：4

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