Prevention of pre-eclampsia after infertility treatment: Preconceptional minimalisation of risk factors

被引：10
作者：
Hurter, Hanna [1 ]
van Breda, Shane Vontelin [3 ]
Vokalova, Lenka [3 ]
Brandl, Marlene [1 ]
Baumann, Marc [4 ]
Hosli, Irene [1 ,3 ]
Huhn, Evelin Annegret [1 ,3 ]
De Geyter, Christian [2 ,3 ]
Rossi, Simona W. [3 ]
Lapaire, Olav [1 ,3 ]
机构：
[1] Univ Basel, Univ Womens Hosp, Dept Obstet, Basel, Switzerland
[2] Univ Basel, Univ Hosp, Reprod Med & Gynecol Endocrinol RME, Vogesenstr 124, CH-4031 Basel, Switzerland
[3] Univ Basel, Univ Hosp, Dept Biomed DBM, Basel, Switzerland
[4] Univ Hosp Bern, Dept Obstet & Gynaecol, Bern, Switzerland
来源：
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM | 2019年 / 33卷 / 01期
关键词：
pre-eclampsia; infertility; obesity; blood pressure; pregnancy; preconception; LOW-DOSE ASPIRIN; PREGNANCY OUTCOMES; MOUSE MODEL; PRAVASTATIN; STATINS; BIRTH; COMPLICATIONS; METAANALYSIS; COHORT; CARE;
D O I：
10.1016/j.beem.2019.05.001
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Although an increased risk of pre-eclampsia in pregnancies conceived after infertility treatment has been reported, it remains unknown whether preconceptional minimalisation of known risk factors would help in preventing pre-eclamsia. Obesity and pre-conceptional blood pressure are discussed as major risks for the development of pre-eclampsia and low doses of aspirins, folic acid, statins and metformin are discussed as potential preventive treatments to decrease the risk of pre-eclampsia. In the present review we discuss whether present-day reproductive medicine could progress towards complication-free pregnancy. (C) 2019 Elsevier Ltd. All rights reserved.
引用
收藏
页码：127 / 132
页数：6
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