Genomic Features of Response to Combination Immunotherapy in Lung Cancer

被引：17
|
作者：
Frueh, Martin [1 ]
Peters, Solange [2 ]
机构：
[1] Cantonal Hosp St Gallen, Dept Med Oncol Hematol, St Gallen, Switzerland
[2] Univ Hosp Lausanne CHUV, Dept Med Oncol, CH-1011 Lausanne, Switzerland
来源：
CANCER CELL | 2018年 / 33卷 / 05期
关键词：
NIVOLUMAB PLUS IPILIMUMAB; MUTATIONAL LANDSCAPE; CTLA-4; BLOCKADE; OPEN-LABEL; MELANOMA;
D O I：
10.1016/j.ccell.2018.04.005
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In this issue of Cancer Cell, Hellmann et al. describe in two clinical trials the importance of tumor mutational burden as an independent predictive marker for outcomes with combination nivolumab plus ipilimumab as first-line therapy in metastatic non-small-cell lung cancer and in relapsed small-cell lung cancer.
引用
收藏
页码：791 / 793
页数：3
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