Merkel cell carcinoma. Case report

被引:1
作者
Pink, Richard [1 ]
Molitor, Martin [2 ,3 ]
Ehrmann, Jiri [3 ,4 ]
Tvrdy, Peter [1 ]
Michl, Petr [1 ]
Pazdera, Jindrich [1 ]
机构
[1] Univ Hosp, Dept Oral & Maxillofacial Surg, Olomouc, Czech Republic
[2] Palacky Univ, Fac Med & Dent, Dept Plast & Aesthet Surg, CR-77147 Olomouc, Czech Republic
[3] Univ Hosp, Olomouc, Czech Republic
[4] Palacky Univ, Fac Med & Dent, Dept Pathol, CR-77147 Olomouc, Czech Republic
来源
BIOMEDICAL PAPERS-OLOMOUC | 2014年 / 158卷 / 01期
关键词
merkel cell carcinoma; immuno supression; diagnosis; treatment; HEAD; NECK;
D O I
10.5507/bp.2012.034
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Background. Merkel cell carcinoma (MCC) is a rare aggressive skin tumour affecting mainly older and immuno suppressed individuals (see our review on MCC in this volume). Aim. This is a case report describing our first experience with Merkel cell carcinoma in an elderly woman on chemo therapy for lymphoma and it covers the diagnosis, treatment and outcome. Methods. We did a radical excision of the soft tissue in the tumor area in conjunction with total paroditectomy and resection of the body of the zygomatic bone by radical block neck dissection. The skin defect was reconstructed myocutaneous free flap by a plastic surgeon. Results and Conclusion. At 12 months follow-up, the MCC had not recurred.
引用
收藏
页码:158 / 160
页数:3
相关论文
共 9 条
[1]  
Brenner B, 2001, CANCER, V91, P1358, DOI 10.1002/1097-0142(20010401)91:7<1358::AID-CNCR1139>3.0.CO
[2]  
2-C
[3]   Merkel cell carcinoma of the head and neck: A retrospective case series [J].
Brissett, AE ;
Olsen, KD ;
Kasperbauer, JL ;
Lewis, JE ;
Goellner, JR ;
Spotts, BE ;
Weaver, AL ;
Strome, SE .
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2002, 24 (11) :982-988
[4]   ESSENTIALS OF MOHS MICROGRAPHIC SURGERY [J].
COTTEL, WI ;
BAILIN, PL ;
ALBOM, MJ ;
BERNSTEIN, G ;
BRAUN, M ;
HANKE, CW ;
SUTNICK, TB ;
SWANSON, NA .
JOURNAL OF DERMATOLOGIC SURGERY AND ONCOLOGY, 1988, 14 (01) :11-13
[5]  
Feng HC, 2008, SCIENCE, V319, P1096, DOI 10.1126/science.1152586
[6]  
GOEPFERT H, 1984, ARCH OTOLARYNGOL, V110, P707
[7]   Merkel cell carcinoma: Changing incidence trends [J].
Hodgson, NC .
JOURNAL OF SURGICAL ONCOLOGY, 2005, 89 (01) :1-4
[8]   Spontaneous regression of Merkel cell carcinoma: a comparative study of TUNEL index and tumor-infiltrating lymphocytes between spontaneous regression and non-regression group [J].
Inoue, T ;
Yoneda, K ;
Manabe, M ;
Demitsu, T .
JOURNAL OF DERMATOLOGICAL SCIENCE, 2000, 24 (03) :203-211
[9]   A study of apoptosis in Merkel cell carcinoma - An immunohistochemical, ultrastructural, DNA ladder, and TUNEL labeling study [J].
Mori, Y ;
Hashimoto, K ;
Tanaka, K ;
Cui, CY ;
Mehregan, DR ;
Stiff, MA .
AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2001, 23 (01) :16-23