Gene therapy: lessons learnt from the past decade

If is more than a decade since the first approved clinical trial to put genes into the tells of human beings was initiated, In that first trial, investigators at the US National Institutes of Health used a modified mouse leukaemia virus to insert a DNA marker into lymphocytes being used to treat cancer(1). A year later, a similar viral technique was used as treatment for two gills who had severe combined immunodeficiency with mutant adenosine deaminase,(2) Ten years and more than 3000 patients later, it is appropriate to ask, "Where are we now?"