Developmental regulation of somite derivatives: muscle, cartilage and tendon

被引：141
|
作者：
Brent, AE [1 ]
Tabin, CJ [1 ]
机构：
[1] Harvard Univ, Sch Med, Dept Genet, Boston, MA 02115 USA
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 2002年 / 12卷 / 05期
关键词：
D O I：
10.1016/S0959-437X(02)00339-8
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Recent research has broadened significantly our understanding of how the somite, a specialized mesodermal structure found in vertebrate embryos, gives rise to the cartilage, muscle and tendon cell lineages. The specification of somite derivatives involves the action of patterning signals secreted from adjacent tissue combined with the activation, in particular somitic compartments, of genes promoting cell lineage specification.
引用
收藏
页码：548 / 557
页数：10
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