Green and Highly Efficient Synthesis of New Bis-benzofurans via Electrochemical Methods under ECECCC Mechanism

被引：15

作者：

Ameri, Mohsen ^{[1
]}

Asghari, Alireza ^{[1
]}

Amoozadeh, Ali ^{[1
]}

Bakherad, Mohammad ^{[2
]}

Nematollahi, Davood ^{[3
]}

机构：

[1] Semnan Univ, Dept Chem, Semnan 35195363, Iran

[2] Shahrood Univ Technol, Coll Chem, Shahrood, Iran

[3] Bu Ali Sina Univ, Fac Chem, Hamadan, Iran

来源：

JOURNAL OF THE ELECTROCHEMICAL SOCIETY | 2014年 / 161卷 / 10期

关键词：

DERIVATIVES;

D O I：

10.1149/2.0371410jes

中图分类号：

O646 [电化学、电解、磁化学];

学科分类号：

081704 ;

摘要：

Oxidation of hydroquinone (1a) has been studied in the presence of methyl cyanoacetate (3a) and ethyl cyanoacetate (3b) as nucleophile in phosphate buffer solution (0.2 M, pH 7) mixed with ethanol as a green solvent (80:20 v:v) using cyclic voltammetry and coulometry, under constant potential. The obtained results indicated that p-quinone derived from electro-oxidation of hydroquinone (1a), participated in 1,4-Michael addition reactions with cyanoacetate derivatives (3a-3b) via ECECCC mechanism (E:electrochemical and C: chemical). In the present study, new benzofuran derivatives were synthesized in good yields and high purity using a facial, one-pot and environmental electrochemical method by 3 carbon electrodes in an undivided cell, without any chemical reagent and hazardous solvents. (C) 2014 The Electrochemical Society. All rights reserved.

引用

页码：G75 / G80

页数：6

共 15 条

[1]

[Anonymous], CHIN CHEM LETT

[2]

[Anonymous], ULMANNS ENCY IND CHE

[3] Synthesis and antitumor activity of new benzoheterocyclic derivatives of distamycin A [J].