VirB Alleviates H-NS Repression of the icsP Promoter in Shigella flexneri from Sites More Than One Kilobase Upstream of the Transcription Start Site

被引：24

作者：

Castellanos, Maria I. ^{[1
]}

Harrison, Dustin J. ^{[1
]}

Smith, Jennifer M. ^{[1
]}

Labahn, Stephanie K. ^{[1
]}

Levy, Karen M. ^{[1
]}

Wing, Helen J. ^{[1
]}

机构：

[1] Univ Nevada, Sch Life Sci, Las Vegas, NV 89154 USA

来源：

JOURNAL OF BACTERIOLOGY | 2009年 / 191卷 / 12期

基金：

美国国家科学基金会;

关键词：

ENTEROINVASIVE ESCHERICHIA-COLI; OUTER-MEMBRANE PROTEASE; VIRULENCE PLASMID; REGULATORY CASCADE; GENE; EXPRESSION; LOCALIZATION; BACTERIA; IDENTIFICATION; ACTIVATION;

D O I：

10.1128/JB.00313-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The icsP promoter of Shigella spp. is repressed by H-NS and derepressed by VirB. Here, we show that an inverted repeat located between positions -1144 and -1130 relative to the icsP transcription start site is necessary for VirB-dependent derepression. The atypical location of this cis-acting site is discussed.

引用

页码：4047 / 4050

页数：4

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