Role of dilatation and curettage performed for spontaneous or induced abortion in the etiology of endometrial thinning

被引：38

作者：

Azumaguchi, Atsushi ^{[1
]}

Henmi, Hirofumi ^{[2
]}

Ohnishi, Hirofumi ^{[3
]}

Endo, Toshiaki ^{[4
]}

Saito, Tsuyoshi ^{[4
]}

机构：

[1] Sapporo Endometrium Res, Sapporo, Hokkaido, Japan

[2] Tonan Hosp, KKR Sapporo Med Ctr, Dept Gynecol & Reprod Endocrinol, Sapporo, Hokkaido, Japan

[3] Sapporo Med Univ, Dept Publ Hlth, Sapporo, Hokkaido, Japan

[4] Sapporo Med Univ, Dept Obstet & Gynecol, Sapporo, Hokkaido, Japan

来源：

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH | 2017年 / 43卷 / 03期

关键词：

dilatation and curettage; endometrium; induced abortion; spontaneous abortion; ultrasonography; ASSISTED REPRODUCTIVE TECHNOLOGY; THICKNESS; HYPOMENORRHEA; INSEMINATION; AMENORRHEA; CYCLES;

D O I：

10.1111/jog.13254

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

AimThe aim of this study was to clarify the role of dilatation and curettage (D&C) performed for spontaneous or induced abortion in the etiology of endometrial thinning. MethodsThis was a retrospective and cross-sectional study of 310 infertile patients from January 2013 through December 2015. Endometrial thickness observed 5-7 days after ovulation in a natural menstrual cycle was correlated with the number of D&C noted in each patient's history. ResultsStudy 1 was an investigation of patients without D&C (group A: n = 232) and patients with D&C performed for spontaneous abortion (group B: n = 46). Study 2 was an investigation of patients in group A and patients with D&C performed for induced abortion (group C: n = 32). A significant negative correlation (P < 0.01) between endometrial thickness and number of D&C was observed in both studies. The mean endometrial thickness of the patients in group A was 10.9 2.1 mm. The mean endometrial thickness of the patients in group B with one and two D&C was 7.9 +/- 2.3 and 6.9 +/- 2.9 mm, respectively. The mean endometrial thickness of the patients in group C with one and two D&C was 9.1 +/- 2.3 and 7.8 +/- 2.0 mm, respectively. There was a tendency toward gradual endometrial thinning following repeated procedures and the number of previous D&C was significantly associated with endometrial thinning (P < 0.001) in both studies. ConclusionD&C performed for spontaneous or induced abortion may play a causal role in endometrial thinning.

引用

页码：523 / 529

页数：7