Management of pediatric snake bites: Are we doing too much?

被引:17
作者
Correa, Jesus A. [1 ]
Fallon, Sara C. [1 ]
Cruz, Andrea T. [2 ]
Grawe, Glenda H. [2 ]
Vu, Phong V. [2 ]
Rubalcava, Daniel M. [2 ]
Kaziny, Brent [2 ]
Naik-Mathuria, Bindi J. [1 ]
Brandt, Mary L. [1 ]
机构
[1] Baylor Coll Med, Michael E DeBakey Dept Surg, Div Pediat Surg, Houston, TX 77030 USA
[2] Baylor Coll Med, Dept Pediat, Sect Emergency Med, Houston, TX 77030 USA
关键词
Pediatric; Envenomation; Snake bite; Animal bite; Antivenom; POLYVALENT IMMUNE FAB; CROTALIDAE POLYVALENT; VENOM; ENVENOMATION;
D O I
10.1016/j.jpedsurg.2014.01.043
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Background: The optimal management of children with snake bite injuries is not well defined. The purpose of this study was to review the use of antivenom, diagnostic tests, and antibiotics in children bitten by venomous snakes in a specific geographic region (Southeast Texas). Methods: This is a retrospective single-center review of all patients with snake bite injury from 1/2006 to 6/2012. An envenomated bite was defined as causing edema, discoloration of the skin, necrosis, or systemic effects. The severity of injury was scored using a novel 4-point scale based on initial physical examination alone. Results: One hundred fifty-one children (mean age 8.4 +/- 4.3 years) were treated for a snake bite. There were no mortalities. Lower extremity injuries were most common (60%). Most bites were from copperheads (43%). Envenomation was evident in 82% (average wound score: 2.61 +/- 0.81). The median hospital stay for admitted patients (79%) was 2 days (range 1-7). Four patients required surgery for complications of the snake bite. Fifty-two children (34%) received CroFab, with one allergic reaction. 22/135 (16%) had evidence of coagulopathy. Seventy-two children (48%) received IV antibiotics. Conclusion: Despite a high rate of envenomated bites in Southeast Texas, significant morbidity is rare. Children with an envenomation score of 1 or 2 are unlikely to be coagulopathic, suggesting that laboratory investigation should be reserved for patients with higher scores. The indications for the administration of CroFab deserve further prospective study. (C) 2014 Elsevier Inc. All rights reserved.
引用
收藏
页码:1009 / 1015
页数:7
相关论文
共 27 条
[1]  
Brazil O.V., 1978, Memorias do Instituto Butantan (Sao Paulo), V40-41, P221
[2]   Rattlesnake venom-induced thrombocytopenia response to antivenin (Crotalidae) polyvalent: A case series [J].
Bush, SP ;
Wu, VH ;
Corbett, SW .
ACADEMIC EMERGENCY MEDICINE, 2000, 7 (02) :181-185
[3]   Pediatric snakebites: lessons learned from 114 cases [J].
Campbell, Brendan T. ;
Corsi, John M. ;
Boneti, Cristiano ;
Jackson, Richard J. ;
Smith, Samuel D. ;
Kokoska, Evan R. .
JOURNAL OF PEDIATRIC SURGERY, 2008, 43 (07) :1338-1341
[4]  
Clark Richard F., 1993, Journal of Emergency Medicine, V11, P583, DOI 10.1016/0736-4679(93)90313-V
[5]   COMPARISON OF A NEW OVINE ANTIGEN-BINDING FRAGMENT (FAB) ANTIVENIN FOR UNITED-STATES CROTALIDAE WITH THE COMMERCIAL ANTIVENIN FOR PROTECTION AGAINST VENOM-INDUCED LETHALITY IN MICE [J].
CONSROE, P ;
EGEN, NB ;
RUSSELL, FE ;
GERRISH, K ;
SMITH, DC ;
SIDKI, A ;
LANDON, JT .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1995, 53 (05) :507-510
[6]  
Corrigan P., 1978, TOXINS ANIMAL PLANT, P457
[7]   Validation of a severity score for the assessment of crotalid snakebite [J].
Dart, RC ;
Hurlbut, KM ;
Garcia, R ;
Boren, J .
ANNALS OF EMERGENCY MEDICINE, 1996, 27 (03) :321-326
[8]   Efficacy, safety, and use of snake antivenoms in the United States [J].
Dart, RC ;
McNally, J .
ANNALS OF EMERGENCY MEDICINE, 2001, 37 (02) :181-188
[9]   Bites of venomous snakes [J].
Gold, BS ;
Dart, RC ;
Barish, RA .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 347 (05) :347-356
[10]   Crotalidae Polyvalent Immune Fab for the Treatment of Pediatric Crotaline Envenomation [J].
Goto, Collin S. ;
Feng, Sing-Yi .
PEDIATRIC EMERGENCY CARE, 2009, 25 (04) :273-282