A fluorescein-derived anthocyanidin-inspired pH sensor

被引：26

作者：

Unciti-Broceta, Asier ^{[1
]}

Yusop, M. Rahimi ^{[1
]}

Richardson, Patricia R. ^{[1
]}

Walton, Jeffrey G. A. ^{[1
]}

Bradley, Mark ^{[1
]}

机构：

[1] Univ Edinburgh, Sch Chem, Edinburgh EH9 3JJ, Midlothian, Scotland

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 26期

关键词：

IN-VIVO; PROBES; INDICATORS; CELLS;

D O I：

10.1016/j.tetlet.2009.03.223

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new multicolor pH-dependent fluorophore was synthesized via Pd-mediated cross-coupling chemistry of the mono-triflate of fluorescein with p-hydroxyphenylboronic acid. The novel indicator, named anthofluorescein, is highly sensitive to pH changes between 7 and 10 and displays a green to red fluorescence shift, making it a Valuable candidate for biological studies. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：3713 / 3715

页数：3

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