Quartz crystal microbalance (QCM) gravimetric sensing of theophylline via molecularly imprinted microporous polypyrrole copolymers

被引：28

作者：

Kim, Jong Min ^{[1
]}

Yang, Jin Chul ^{[2
]}

Park, Jin Young ^{[3
]}

机构：

[1] Dong A Univ, Dept Chem Engn, Pusan 604714, South Korea

[2] Kyungpook Natl Univ, Sch Appl Chem Engn, Taegu 702701, South Korea

[3] Kyungpook Natl Univ, Dept Polymer Sci Engn, Taegu 702701, South Korea

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2015年 / 206卷

基金：

新加坡国家研究基金会;

关键词：

Molecularly imprinted conducting polymer(MICP); Theophylline Cyclic voltammetry; Colloidal lithography; Porous structure; Polystyrene colloids; AMINO-ACID; POLYMER; RECOGNITION; TEMPLATE; SENSOR; SELECTIVITY; SEPARATION; FILMS;

D O I：

10.1016/j.snb.2014.09.047

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In this paper, we developed a novel molecularly imprinted conducting polymer (MICP) system consisting of porous poly(pyrrole-co-pyrrole-3-carboxylic acid) copolymer matrices for the recognition of theophylline (THEO), a drug molecule. Various porous MICP (p-MICP) films were made using colloidal lithography and examined via gravimetric technique [e.g. gold quartz crystal microbalances (QCMs)]. They showed faster sensing response than a planar MICP film due to the increased THEO binding sites obtained from porous structures. Thus, this lithographical approach to MICP sensors can enable the rebind of a specific template to be increased to achieve improved sensor capacity. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：50 / 55

页数：6

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