Renal phosphate wasting due to tumor-induced osteomalacia: a frequently delayed diagnosis

被引：19

作者：

Gore, M. Odette ^{[1
,2
]}

Welch, Brian J. ^{[1
,2
]}

Geng, Weidong ^{[1
,2
]}

Kabbani, Wareef ^{[3
]}

Maalouf, Naim M. ^{[1
,2
]}

Zerwekh, Joseph E. ^{[1
,2
]}

Moe, Orson W. ^{[1
,2
]}

Sakhaee, Khashayar ^{[1
,2
]}

机构：

[1] Univ Texas SW Med Ctr Dallas, Charles & Jane Pak Ctr Mineral Metab & Clin Res, Dallas, TX 75390 USA

[2] Univ Texas SW Med Ctr Dallas, Dept Internal Med, Dallas, TX 75390 USA

[3] Univ Texas SW Med Ctr Dallas, Dept Pathol, Dallas, TX 75390 USA

来源：

KIDNEY INTERNATIONAL | 2009年 / 76卷 / 03期

基金：

美国国家卫生研究院;

关键词：

ONCOGENIC OSTEOMALACIA; TERTIARY HYPERPARATHYROIDISM; MESENCHYMAL TUMORS; HOMEOSTASIS; FIBROBLAST-GROWTH-FACTOR-23; OCTREOTIDE; FGF23; PHEX;

D O I：

10.1038/ki.2008.355

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

In our patient, TIO remained undiagnosed for several years. Careful metabolic evaluation and extensive investigations eventually led to the diagnosis, and TIO was cured by surgical removal of the offending tumor. We emphasize the importance of determining serum phosphorus and TmP/ GFR and considering TIO early in the differential diagnosis of unexplained persistent bone pain, apparent joint pain, muscle weakness, and spontaneous fractures. © 2009 International Society of Nephrology.

引用

页码：342 / 347

页数：6

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