Societal preference values for advanced melanoma health states in the United Kingdom and Australia

被引:60
作者
Beusterien, K. M. [1 ]
Szabo, S. M. [2 ]
Kotapati, S. [3 ]
Mukherjee, J. [3 ]
Hoos, A. [3 ]
Hersey, P.
Middleton, M. R. [4 ]
Levy, A. R. [2 ,5 ]
机构
[1] Oxford Outcomes Inc, Bethesda, MD 20814 USA
[2] Oxford Outcomes Ltd, Vancouver, BC V6B 1P1, Canada
[3] Bristol Myers Squibb Co, Wallingford, CT 06492 USA
[4] Churchill Hosp, Canc Res UK Med Oncol Unit, Oxford OX3 7LJ, England
[5] Univ British Columbia, Dept Hlth Care & Epidemiol, Vancouver, BC V6T 1Z4, Canada
关键词
melanoma; utility; standard gamble; preferences; QUALITY-OF-LIFE; ADJUVANT INTERFERON-ALPHA-2B; METASTATIC MELANOMA; CUTANEOUS MELANOMA; COST-EFFECTIVENESS; UTILITIES; SCORES; ALPHA;
D O I
10.1038/sj.bjc.6605187
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
BACKGROUND: No studies measure preference-based utilities in advanced melanoma that capture both intended clinical response and unintended toxicities associated with treatment. METHODS: Using standard gamble, utilities were elicited from 140 respondents in the United Kingdom and Australia for 13 health states. RESULTS: Preferences decreased with reduced treatment responsiveness and with increasing toxicity. CONCLUSION: These general population utilities can be incorporated into treatment-specific cost-effectiveness evaluations. British Journal of Cancer (2009) 101, 387-389. doi:10.1038sj.bjc.6605187 www.bjcancer.com Published online 14 July 2009 (C) 2009 Cancer Research UK
引用
收藏
页码:387 / 389
页数:3
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