The utility of magnetic resonance imaging lesion combinations in the sacroiliac joints for diagnosing patients with axial spondyloarthritis. A prospective study of 204 participants including post-partum women, patients with disc herniation, cleaning staff, runners and healthy persons (vol 59, pg 3237, 2020)

被引：0

作者：

Seven, Sengul ^{[1
,2
]}

Ostergaard, Mikkel ^{[1
,2
]}

Morsel-Carlsen, Lone ^{[3
]}

Sorensen, Inge Juul ^{[1
]}

Bonde, Birthe ^{[4
]}

Thamsborg, Gorm ^{[1
]}

Lykkegaard, Jens Jorgen ^{[1
]}

Hendricks, Oliver ^{[5
]}

Jorgensen, Niklas Rye ^{[6
,7
]}

Pedersen, Susanne Juhl ^{[1
,2
]}

机构：

[1] Rigshosp Glostrup, Copenhagen Ctr Arthrit Res, Ctr Rheumatol & Spine Dis, Ctr Head & Orthoped, Valdemar Hansens Vej 17, DK-2600 Glostrup, Denmark

[2] Univ Copenhagen, Dept Clin Med, Copenhagen, Denmark

[3] Rigshosp Glostrup, Dept Radiol, Glostrup, Denmark

[4] Birthe Bonde Clin Physiotherapy, Copenhagen, Denmark

[5] Danish Hosp Rheumat Dis, Sonderborg, Denmark

[6] Univ Southern Denmark, Odense, Denmark

[7] Rigshosp Glostrup, Dept Clin Biochem, Glostrup, Denmark

来源：

RHEUMATOLOGY | 2020年 / 59卷 / 11期

关键词：

Axial spondyloarthritis; Inflammation; Magnetic resonance imaging; Post-partum women; Sacroiliac joints;

D O I：

10.1093/rheumatology/keaa349

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objectives. To investigate the diagnostic utility of different combinations of SI joint MRI lesions for differentiating patients with axial SpA (axSpA) from other conditions with and without buttock/pelvic pain. Methods. A prospective cross-sectional study included patients with axSpA (n ¼ 41), patients with lumbar disc herniation (n ¼ 25), women with (n ¼ 46) and without (n ¼ 14) post-partum (birth within 4-16 months) buttock/pelvic pain and cleaning assistants (n ¼ 26), long-distance runners (n ¼ 23) and healthy men (n ¼ 29) without pain. Two independent readers assessed SI joint MRI lesions according to the Spondyloarthritis Research Consortium of Canada MRI definitions and pre-defined MRI lesion combinations with bone marrow oedema (BME) and fat lesions (FAT), respectively. Statistical analyses included the proportion of participants with scores above certain thresholds, sensitivity, specificity, positive and negative predictive values and likelihood ratios. Results. BME adjacent to the joint space (BME@joint space) was most frequent in axSpA (63.4%), followed by women with post-partum pain (43.5%), but was present in nearly all groups. BME adjacent to fat lesions (BME@FAT) and BME adjacent to erosions (BME@erosion) were only present in axSpA patients and in women with post-partum pain, but scores >3 and >4, respectively, were only seen in axSpA patients. FAT@erosion was exclusively recorded in axSpA patients. FAT@joint space and FAT@sclerosis were present in most groups, but with higher scores in the axSpA group. Conclusion. BME@joint space and FAT@joint space were frequent in axSpA but also in other conditions, reducing the diagnostic utility. FAT@erosion, and BME@FAT, BME@erosion and FAT@sclerosis above certain thresholds, were exclusively seen in axSpA patients and may thus have diagnostic utility in the differentiation of axSpA from other conditions. © The Author(s) 2020. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.com

引用

页码：3585 / 3585

页数：1