Platelet-rich plasma: New clinical application A pilot study for treatment of jumper's knee

被引：202

作者：

Kon, Elizaveta ^{[1
]}

Filardo, Giuseppe ^{[1
]}

Delcogliano, Marco ^{[1
]}

Lo Presti, Mirco ^{[1
]}

Russo, Alessandro ^{[1
]}

Bondi, Alice ^{[1
]}

Di Martino, Alessandro ^{[1
]}

Cenacchi, Annarita ^{[2
]}

Fornasari, Pier Maria ^{[2
]}

Marcacci, Maurilio ^{[1
]}

机构：

[1] Rizzoli Orthopaed Inst, Biomech Lab, Dept Orthopaed & Sports Trauma, I-40136 Bologna, Italy

[2] Rizzoli Orthopaed Inst, Immunohaematol & Transfus Med Serv, I-40136 Bologna, Italy

来源：

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED | 2009年 / 40卷 / 06期

关键词：

Platelet-rich plasma; Jumper's knee; Patellar tendinosis; ECCENTRIC DECLINE SQUAT; PATELLAR TENDINOPATHY; VOLLEYBALL PLAYERS; ACHILLES-TENDON; OPERATIVE TREATMENT; FIBRIN MATRICES; PARTIAL RUPTURE; GROWTH-FACTORS; LIGAMENT; PROLIFERATION;

D O I：

10.1016/j.injury.2008.11.026

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

This study describes a simple, low-cost, minimally invasive way to apply PRP growth factors to chronic patellar tendinosis; 20 male athletes with a mean history of 20.7 months of pain received treatment, and outcomes were prospectively evaluated at 6 months follow-up. No severe adverse events were observed, and statistically significant improvements in all scores were recorded. The results suggest that this method may be safely used for the treatment of jumper's knee, by aiding the regeneration of tissue which otherwise has low healing potential. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：598 / 603

页数：6

共 31 条

[1] Etiology, diagnosis, and treatment of tendonitis: an analysis of the literature [J].

Almekinders, LC ;

Temple, JD .

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 1998, 30 (08) :1183-1190

[2] Autologous fibrin matrices: A potential source of biological mediators that modulate tendon cell activities [J].

Anitua, E ;

Sanchez, M ;

Nurden, AT ;

Zalduendo, M ;

de la Fuente, M ;

Orive, G ;

Azofra, J ;

Andia, I .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2006, 77A (02) :285-293

[3] Autologous preparations rich in growth factors promote proliferation and induce VEGF and HGF production by human tendon cells in culture [J].

Anitua, E ;

Andía, I ;

Sanchez, M ;

Azofra, J ;

Zalduendo, MD ;

de la Fuente, M ;

Nurden, P ;

Nurden, AT .

JOURNAL OF ORTHOPAEDIC RESEARCH, 2005, 23 (02) :281-286

[4] Autologous platelets as a source of proteins for healing and tissue regeneration [J].

Anitua, E ;

Andia, I ;

Ardanza, B ;

Nurden, P ;

Nurden, AT .

THROMBOSIS AND HAEMOSTASIS, 2004, 91 (01) :4-15

[5] Platelet concentrate injection improves Achilles tendon repair in rats [J].

Aspenberg, P ;

Virchenko, O .

ACTA ORTHOPAEDICA SCANDINAVICA, 2004, 75 (01) :93-99

[6] Surgical treatment compared with eccentric training for patellar tendinopathy (jumper's knee) - A randomized, controlled trial [J].

Bahr, Roald ;

Fossan, Bjorn ;

Loken, Sverre ;

Engebretsen, Lars .

JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2006, 88A (08) :1689-1698

[7] Anthropometry, physical performance, and ultrasound patellar tendon abnormality in elite junior basketball players: a cross-sectional study [J].

Cook, JL ;

Kiss, ZS ;

Khan, KM ;

Purdam, CR ;

Webster, KE .

BRITISH JOURNAL OF SPORTS MEDICINE, 2004, 38 (02) :206-209

[8] A cross sectional study of 100 athletes with jumper's knee managed conservatively and surgically [J].

Cook, JL ;

Khan, KM ;

Harcourt, PR ;

Grant, M ;

Young, DA ;

Bonar, SF .

BRITISH JOURNAL OF SPORTS MEDICINE, 1997, 31 (04) :332-336

[9] Tissue engineering of flexor tendons: Optimization of tenocyte proliferation using growth factor supplementation [J].

Costa, Melinda Aliza ;

Wu, Cindy ;

Pham, Bryant Vu ;

Chong, Alphonsus Khin Sze ;

Pham, Hung Minh ;

Chang, James .

TISSUE ENGINEERING, 2006, 12 (07) :1937-1943

[10] Can platelet-rich plasma enhance tendon repair? A cell culture study [J].

de Mos, Marieke ;

van der Windt, Anna E. ;

Jahr, Holger ;

van Schie, Hans T. M. ;

Weinans, Harrie ;

Verhaar, Jan A. N. ;

van Osch, Gerjo J. V. M. .

AMERICAN JOURNAL OF SPORTS MEDICINE, 2008, 36 (06) :1171-1178

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