Beyond Reppe: Building Substituted Arenes by [2+2+2] Cycloadditions of Alkynes

被引：256

作者：

Galan, Brandon R. ^{[1
]}

Rovis, Tomislav ^{[1
]}

机构：

[1] Colorado State Univ, Dept Chem, Ft Collins, CO 80523 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 16期

关键词：

arenes; cycloaddition; homogeneous catalysis; multicomponent reactions; REGIOSELECTIVE INTERMOLECULAR CYCLOTRIMERIZATION; CATIONIC RHODIUM(I)/MODIFIED BINAP; ONE-POT SYNTHESIS; BENZENE-DERIVATIVES; ORGANIC-SYNTHESIS; COMPLEXES; CONSTRUCTION; CATALYST; ACETYLENES; EFFICIENT;

D O I：

10.1002/anie.200804651

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Synthetic sequel: The transition-metal-catalyzed [2+2+2] cycloaddition is an established method for the construction of carbocyclic frameworks but is often plagued by poor selectivity. Recent literature paints a promising picture - a more general metal-catalyzed [2+2+2] cycloaddition can be accomplished intermolecularly using three separate alkynes to furnish highly substituted arenas (see scheme). © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2830 / 2834

页数：5

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