Modern GERD Treatment: Feasibility of Minimally Invasive Esophageal Sphincter Augmentation

被引:0
作者
Schwameis, Katrin [1 ,3 ,4 ]
Schwameis, Michael [2 ]
Zoerner, Barbara [1 ]
Lenglinger, Johannes [1 ]
Asari, Reza [1 ,3 ,4 ]
Riegler, Franz Martin [1 ]
Schoppmann, Sebastian Friedrich [1 ,3 ,4 ]
机构
[1] Med Univ Vienna, Dept Surg, A-1090 Vienna, Austria
[2] Med Univ Vienna, Dept Clin Pharmacol, A-1090 Vienna, Austria
[3] Med Univ Vienna, Upper GI Res Grp, A-1090 Vienna, Austria
[4] Med Univ Vienna, Comprehens Canc Ctr Vienna, CCC GET Unit, A-1090 Vienna, Austria
关键词
LINX (TM); GERD; reflux; esophageal sphincter; laparoscopy; BARRETTS-ESOPHAGUS; DEVICE; RISK;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: Gastroesophageal reflux disease (GERD) is a common chronic disease requiring adequate treatment since it represents one major cause of development of Barrett's esophagus and eventually carcinoma. Novel laparoscopic magnetic sphincter augmentation for GERD was evaluated prospectively. Patients and Methods: A total of 23 patients with GERD underwent minimally invasive implantation of LINX (TM) Reflux Management System. Primary outcome measures were overall feasibility, short-term procedure safety and efficacy. Secondary GERD-related quality of life was assessed. Results: All implantations were performed without serious adverse events. A significant decrease in all major GERD complaints were found: heartburn: 96%-22% (p<0.001); bloating: 70%-30% (p=0.006); respiratory complaints: 57%-17% (p=0.039); sleep disturbance: 65%-4% (p<0.001). A four-week follow-up reduction of >= 50% of proton pump inhibitor (PPI) dose was achieved in over 80% of patients. Self-limiting difficulty in swallowing was found in 70% within four weeks. One patient required for endoscopic dilation. GERD-related quality of life improved significantly. Conclusion: LINX (TM) implantation is a standardized, technically simple, safe and well-tolerated expeditious procedure.
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收藏
页码:2341 / 2348
页数:8
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