Prevalence of adhesive genes among uropathogenic Escherichia coli strains isolated from patients with urinary tract infection in Mangalore

被引：10

作者：

Shetty, A. V. ^{[1
]}

Kumar, S. H. ^{[2
]}

Shekar, M. ^{[3
]}

Shetty, A. K. ^{[4
]}

Karunasagar, I. ^{[3
]}

机构：

[1] NITTE Univ, KS Hegde Med Acad, Dept Microbiol, Mangalore, Karnataka, India

[2] Cent Inst Fisheries Educ, Harvest & Post Harvest Technol Div, Bombay, Maharashtra, India

[3] Anim & Fisheries Sci Univ, Coll Fisheries, Karnataka Vet, Dept Fishery Microbiol, Mangalore, Karnataka, India

[4] Wake Forest Univ, Bowman Gray Sch Med, Dept Pediat, Winston Salem, NC 27103 USA

来源：

INDIAN JOURNAL OF MEDICAL MICROBIOLOGY | 2014年 / 32卷 / 02期

关键词：

Adhesive genes; congo red binding; Escherichia; coli; haemolysin; urinary tract infection; UPEC; VIRULENCE FACTORS; ENCODING OPERONS; SFA; PAP; AFA;

D O I：

10.4103/0255-0857.129812

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The study was carried out to detect the adhesive genes pap (pyelonephritis associated pili), sfa (S fimbrial adhesin) and afa (afimbrial adhesin) from Escherichia coli strains isolated in patients diagnosed with urinary tract infection (UTI). A total of 23% of the isolates were positive for pap, sfa and afa genes with a prevalence of 60.87% (14/23), 39.1% (9/23) and 39.1% (9/23), respectively. Prevalence of multiple adhesive genes was 8.7% (2/23) for pap and afa, 30.43% (7/23) for pap and sfa. Significant numbers of isolates were positive for Congo red binding (80%) and haemolysin production 60%. The prevalence of multiple adhesive genes indicate the potential to adhere and subsequently cause a systemic infection among UTI patients.

引用

页码：175 / 178

页数：4

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