C35 terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines

被引：18
作者：
Hsieh, Chin-Lin
Tseng, Mei-Huims
Shao, Yi-Yuan
Chang, Jang-Yang
Kuo, Ching-Chuan
Chang, Chi-Yen
Kuo, Yueh-Hsiung [1 ]
机构：
[1] Natl Taiwan Univ, Dept Chem, Taipei 106, Taiwan
[2] Taipei Municipal Teachers Univ, Dept Sci Educ, Taipei 106, Taiwan
[3] Shih Chien Univ, Dept Food Sci Nutr & Nutraceut Biotechnol, Taipei 106, Taiwan
[4] Natl Hlth Res Inst, Inst Canc Res, Taipei 114, Taiwan
[5] Natl Def Med Ctr, Tri Serv Gen Hosp, Dept Med, Div Hematol Oncol, Taipei 114, Taiwan
[6] Acad Sinica, Inst BioAgr Sci, Taipei 115, Taiwan
来源：
JOURNAL OF NATURAL PRODUCTS | 2006年 / 69卷 / 11期
关键词：
D O I：
10.1021/np0600550
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Ferrugicadinol (1) and ferrugieudesmol (2), two new compounds with a unique C-35 terpene skeleton, were isolated from the bark of Calocedrus macrolepis var. formosana. Their structures were elucidated principally from spectroscopic evidence. The two new C-35 terpenes showed cytotoxicity against human oral epidermoid carcinoma KB cells with IC50 values ranging from 11 to 14 mu M.
引用
收藏
页码：1611 / 1613
页数：3
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