Changing Perspectives on the Perinatal Management of Isolated Congenital Diaphragmatic Hernia in Europe

被引：59
作者：
Deprest, Jan A. [1 ]
Gratacos, Eduardo [2 ]
Nicolaides, Kypros [3 ]
Done, Elise [1 ]
Van Mieghem, Tim [1 ]
Gucciardo, Leonardo [1 ]
Claus, Filip [4 ]
Debeer, Anne [1 ]
Allegaert, Karel [1 ]
Reiss, Irwin [5 ,6 ]
Tibboel, Dick [5 ,6 ]
机构：
[1] Univ Hosp Gasthuisberg, Woman & Child Div, Fetal Med Unit, B-3000 Louvain, Belgium
[2] Hosp Clin Barcelona, Dept Obstet, Barcelona, Spain
[3] Kings Coll Hosp London, Harris Birthright Ctr Fetal Med, London, England
[4] Univ Hosp Gasthuisberg, Div Med Imaging, B-3000 Louvain, Belgium
[5] Sophia Childrens Univ Hosp, Erasmus Med Ctr, Dept Intens Care, Rotterdam, Netherlands
[6] Sophia Childrens Univ Hosp, Erasmus Med Ctr, Dept Pediat Surg, Rotterdam, Netherlands
来源：
CLINICS IN PERINATOLOGY | 2009年 / 36卷 / 02期
关键词：
Congenital diaphragmatic hernia; Prenatal diagnosis; Fetal tracheal occlusion; Prediction of outcome; Neonatal management; ENDOSCOPIC TRACHEAL OCCLUSION; FETAL LUNG-VOLUME; PULMONARY-ARTERY DIAMETERS; INHALED NITRIC-OXIDE; TO-HEAD RATIO; PRENATAL PREDICTION; CLINICAL-EXPERIENCE; LIVER HERNIATION; RANDOMIZED-TRIAL; SURVIVAL RATE;
D O I：
10.1016/j.clp.2009.03.004
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Congenital diaphragmatic hernia (CDH) should be diagnosed in the prenatal period and prompt referral to a tertiary referral center for imaging, genetic testing, and multidisciplinary counseling. Individual prediction of prognosis is based on the absence of additional anomalies, lung size, and liver herniation. In severe cases, a prenatal endotracheal balloon procedure is currently being offered at specialized centers. Fetal intervention is now also offered to milder cases within a trial, hypothesizing that this may reduce the occurrence of bronchopulmonary dysplasia in survivors. Postnatal management has been standardized by European high-volume centers for the purpose of this and other trials.
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页码：329 / +
页数：20
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