Changing Perspectives on the Perinatal Management of Isolated Congenital Diaphragmatic Hernia in Europe

被引：59

作者：

Deprest, Jan A. ^{[1
]}

Gratacos, Eduardo ^{[2
]}

Nicolaides, Kypros ^{[3
]}

Done, Elise ^{[1
]}

Van Mieghem, Tim ^{[1
]}

Gucciardo, Leonardo ^{[1
]}

Claus, Filip ^{[4
]}

Debeer, Anne ^{[1
]}

Allegaert, Karel ^{[1
]}

Reiss, Irwin ^{[5
,6
]}

Tibboel, Dick ^{[5
,6
]}

机构：

[1] Univ Hosp Gasthuisberg, Woman & Child Div, Fetal Med Unit, B-3000 Louvain, Belgium

[2] Hosp Clin Barcelona, Dept Obstet, Barcelona, Spain

[3] Kings Coll Hosp London, Harris Birthright Ctr Fetal Med, London, England

[4] Univ Hosp Gasthuisberg, Div Med Imaging, B-3000 Louvain, Belgium

[5] Sophia Childrens Univ Hosp, Erasmus Med Ctr, Dept Intens Care, Rotterdam, Netherlands

[6] Sophia Childrens Univ Hosp, Erasmus Med Ctr, Dept Pediat Surg, Rotterdam, Netherlands

来源：

CLINICS IN PERINATOLOGY | 2009年 / 36卷 / 02期

关键词：

Congenital diaphragmatic hernia; Prenatal diagnosis; Fetal tracheal occlusion; Prediction of outcome; Neonatal management; ENDOSCOPIC TRACHEAL OCCLUSION; FETAL LUNG-VOLUME; PULMONARY-ARTERY DIAMETERS; INHALED NITRIC-OXIDE; TO-HEAD RATIO; PRENATAL PREDICTION; CLINICAL-EXPERIENCE; LIVER HERNIATION; RANDOMIZED-TRIAL; SURVIVAL RATE;

D O I：

10.1016/j.clp.2009.03.004

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Congenital diaphragmatic hernia (CDH) should be diagnosed in the prenatal period and prompt referral to a tertiary referral center for imaging, genetic testing, and multidisciplinary counseling. Individual prediction of prognosis is based on the absence of additional anomalies, lung size, and liver herniation. In severe cases, a prenatal endotracheal balloon procedure is currently being offered at specialized centers. Fetal intervention is now also offered to milder cases within a trial, hypothesizing that this may reduce the occurrence of bronchopulmonary dysplasia in survivors. Postnatal management has been standardized by European high-volume centers for the purpose of this and other trials.

引用

页码：329 / +

页数：20

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