An update on therapeutic drug monitoring for antiretroviral drugs

被引：66
|
作者：
Back, David [1 ]
Gibbons, Sara [1 ]
Khoo, Saye [1 ]
机构：
[1] Univ Liverpool, Pharmacol Res Labs, Liverpool L69 3GF, Merseyside, England
来源：
THERAPEUTIC DRUG MONITORING | 2006年 / 28卷 / 03期
关键词：
therapeutic drug monitoring; inhibitory quotients; patient outcome; randomized controlled trials; consensus statements;
D O I：
10.1097/01.ftd.0000211825.57984.41
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
There is an increasing uptake of TDM of antiretroviral drugs, particularly in Europe. There is consensus that current antiretroviral drugs meet most of the criteria of drugs that can be considered as candidates for a TDM strategy. This review examines the pharmacokinetic-pharmacodynamic relationship for protease inibitors and non nucleoside reverse transcriptase inhibitor, give an overview of the published randomised clinical trials and then summarises the scenarios for use of TDM. Finally the development of the inhibitory quotient (IQ) concept is discussed.
引用
收藏
页码：468 / 473
页数：6
相关论文
共 50 条
  • [31] Stopping antiretroviral therapy: role for therapeutic drug monitoring
    Tommasi, Chiara
    Nicastri, Emanuele
    Corpolongo, Angela
    Ivanovic, Jelena
    Notari, Stefania
    Ascenzi, Paolo
    Andreoni, Massimo
    Narciso, Pasquale
    AIDS, 2008, 22 (02) : 315 - 316
  • [32] THERAPEUTIC DRUG-MONITORING IN SALIVA - AN UPDATE
    DROBITCH, RK
    SVENSSON, CK
    CLINICAL PHARMACOKINETICS, 1992, 23 (05) : 365 - 379
  • [33] Pros and cons of therapeutic drug monitoring of antiretroviral agents
    Burger, DM
    Aarnoutse, RE
    Hugen, PWH
    CURRENT OPINION IN INFECTIOUS DISEASES, 2002, 15 (01) : 17 - 22
  • [34] Therapeutic Drug Monitoring in the Treatment of Tuberculosis: An Update
    Alsultan, Abdullah
    Peloquin, Charles A.
    DRUGS, 2014, 74 (08) : 839 - 854
  • [35] Therapeutic drug monitoring in highly active antiretroviral therapy
    Liu, Xia
    Ma, Qing
    Zhang, Fujie
    EXPERT OPINION ON DRUG SAFETY, 2010, 9 (05) : 743 - 758
  • [36] Bio-analytical Assay Methods used in Therapeutic Drug Monitoring of Antiretroviral Drugs-A Review
    Charbe, Nitin B.
    Zacconi, Flavia C.
    Amnerkar, Nikhil
    Ramesh, B.
    Tambuwala, Murtaza M.
    Clementi, Emilio
    CURRENT DRUG THERAPY, 2019, 14 (01) : 16 - 57
  • [37] Bioanalytical issues in patient-friendly sampling methods for therapeutic drug monitoring: focus on antiretroviral drugs
    ter Heine, R.
    Beijnen, J. H.
    Huitema, A. D. R.
    BIOANALYSIS, 2009, 1 (07) : 1329 - 1338
  • [38] Therapeutic Drug MonitoringAn Aid to Optimising Response to Antiretroviral Drugs?
    Rob E. Aarnoutse
    Jonathan M. Schapiro
    Charles A.B. Boucher
    Yechiel A. Hekster
    David M. Burger
    Drugs, 2003, 63 : 741 - 753
  • [39] Therapeutic drug monitoring and pharmacogenetics of psychotropic drugs
    不详
    CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2004, 42 (10) : A116 - A116
  • [40] Overview of therapeutic drug monitoring and biotechnologic drugs
    Wolf, BA
    THERAPEUTIC DRUG MONITORING, 1996, 18 (04) : 402 - 404
12345