The progression of acute to chronic pain, also known as pain chronification, remains incompletely understood. Biologic factors involved in this transition include central sensitization, neuroplastic changes, altered pain modulation, and changes to the "neuromatrix.'' Chronic pain may involve irreversible pathophysiologic changes, so interrupting the cascade of events that allows acute pain to advance to chronic pain is of crucial importance. This involves recognition and prompt treatment of acute pain, better awareness and application of evidence-based guidelines on pain management by all clinicians (not just pain specialists), and patient education. By interrupting nociceptive input in acute pain conditions, it might be possible to prevent transition to chronic pain syndromes. (C) 2014 by the American Society for Pain Management Nursing
机构:
Brigham & Womens Hosp, Dept Anesthesiol Perioperat & Pain Med, 75 Francis St, Boston, MA 02115 USABrigham & Womens Hosp, Dept Anesthesiol Perioperat & Pain Med, 75 Francis St, Boston, MA 02115 USA
Pak, Daniel J.
Yong, R. Jason
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机构:
Brigham & Womens Hosp, Dept Anesthesiol Perioperat & Pain Med, 75 Francis St, Boston, MA 02115 USABrigham & Womens Hosp, Dept Anesthesiol Perioperat & Pain Med, 75 Francis St, Boston, MA 02115 USA
Yong, R. Jason
Kaye, Alan David
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Louisiana State Univ, Sch Med, Dept Anesthesiol, New Orleans, LA 70112 USABrigham & Womens Hosp, Dept Anesthesiol Perioperat & Pain Med, 75 Francis St, Boston, MA 02115 USA
Kaye, Alan David
Urman, Richard D.
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Brigham & Womens Hosp, Dept Anesthesiol Perioperat & Pain Med, 75 Francis St, Boston, MA 02115 USABrigham & Womens Hosp, Dept Anesthesiol Perioperat & Pain Med, 75 Francis St, Boston, MA 02115 USA
机构:
McLean Hosp, Boston Childrens Hosp, Ctr Pain & Brain, Boston, MA USA
Massachusetts Hosp, Boston Childrens Hosp, Ctr Pain & Brain, Boston, MA USA
Boston Childrens Hosp, Dept Anesthesia, Boston, MA USA
McLean Hosp, Dept Psychiat, Boston, MA USA
Massachusetts Hosp, Dept Psychiat, Boston, MA USA
Massachusetts Hosp, Dept Radiol, Boston, MA USAMcLean Hosp, Boston Childrens Hosp, Ctr Pain & Brain, Boston, MA USA
Borsook, David
Youssef, Andrew M.
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机构:
McLean Hosp, Boston Childrens Hosp, Ctr Pain & Brain, Boston, MA USA
Massachusetts Hosp, Boston Childrens Hosp, Ctr Pain & Brain, Boston, MA USAMcLean Hosp, Boston Childrens Hosp, Ctr Pain & Brain, Boston, MA USA
Youssef, Andrew M.
Simons, Laura
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Stanford Univ, Dept Anesthesia, Palo Alto, CA 94304 USAMcLean Hosp, Boston Childrens Hosp, Ctr Pain & Brain, Boston, MA USA
Simons, Laura
Elman, Igor
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Vet Adm, Dayton, OH USAMcLean Hosp, Boston Childrens Hosp, Ctr Pain & Brain, Boston, MA USA
Elman, Igor
Eccleston, Christopher
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机构:
Univ Bath, Ctr Pain Res, Bath, Avon, England
Univ Ghent, Dept Clin & Hlth Psychol, Ghent, BelgiumMcLean Hosp, Boston Childrens Hosp, Ctr Pain & Brain, Boston, MA USA