A novel pedigree with heterozygous germline RUNX1 mutation causing familial MDS-related AML: can these families serve as a multistep model for leukemic transformation?

被引:36
作者
Ripperger, T. [1 ]
Steinemann, D. [1 ]
Goehring, G. [1 ]
Finke, J. [2 ]
Niemeyer, C. M. [3 ]
Strahm, B. [3 ]
Schlegelberger, B. [1 ]
机构
[1] Hannover Med Sch, Inst Cell & Mol Pathol, D-3000 Hannover, Germany
[2] Univ Freiburg, Dept Hematol & Oncol, Freiburg, Germany
[3] Univ Freiburg, Dept Pediat & Adolescent Med, Div Pediat Hematol Oncol, Freiburg, Germany
关键词
ACUTE MYELOGENOUS LEUKEMIA; POINT MUTATIONS; CELLS; GENE;
D O I
10.1038/leu.2009.87
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1364 / 1366
页数:4
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