Mitochondrial disease mimicking polymyositis: A case report

被引:5
作者
Corrado, A
Cantatore, FP
Serlenga, L
Amati, A
Petruzzella, V
Lapadula, G
机构
[1] Univ Bari, Bari, Italy
[2] Univ Foggia, Foggia, Italy
关键词
Kearns-Sayre syndrome; mitochondriopathy; myositis;
D O I
10.1007/s100670200110
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The authors report on a 34-year-old woman who had developed severe weakness and reduction in grip strength in both upper and lower limbs. Laboratory blood tests revealed increased levels of muscle enzyme. The presence of progressive bilateral ptosis and external ophthalmoplegia raised the suspicion of a mitochondrial disease, subsequently confirmed by deltoid biopsy and genetic analysis of mitochondrial DNA that showed a deletion indicative of Keams-Sayre syndrome. In this report we emphasise the need for a differential diagnosis between myositis and other myopathics, particularly the mitochondrial ones.
引用
收藏
页码:411 / 414
页数:4
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