Advances in structural genomics

被引：109
作者：
Teichmann, SA
Chothia, C
Gerstein, M
机构：
[1] MRC, Mol Biol Lab, Cambridge CB2 2QH, England
[2] Yale Univ, Dept Mol Biophys & Biochem, New Haven, CT 06520 USA
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 1999年 / 9卷 / 03期
关键词：
D O I：
10.1016/S0959-440X(99)80053-0
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
New computational techniques have allowed protein folds to be assigned to all or parts of between a quarter (Caenorhabditis elegans) and a half (Mycoplasma genitalium) of the individual protein sequences in different genomes. These assignments give a new perspective on domain structures, gene duplications, protein families and protein folds in genome sequences.
引用
收藏
页码：390 / 399
页数：10
相关论文
共 60 条
[1]   Gapped BLAST and PSI-BLAST: a new generation of protein database search programs [J].
Altschul, SF ;
Madden, TL ;
Schaffer, AA ;
Zhang, JH ;
Zhang, Z ;
Miller, W ;
Lipman, DJ .
NUCLEIC ACIDS RESEARCH, 1997, 25 (17) :3389-3402
[2]   BASIC LOCAL ALIGNMENT SEARCH TOOL [J].
ALTSCHUL, SF ;
GISH, W ;
MILLER, W ;
MYERS, EW ;
LIPMAN, DJ .
JOURNAL OF MOLECULAR BIOLOGY, 1990, 215 (03) :403-410
[3]  
Arkin IT, 1997, PROTEINS, V28, P465, DOI 10.1002/(SICI)1097-0134(199708)28:4<465::AID-PROT1>3.0.CO
[4]  
2-9
[5]   How many membrane proteins are there? [J].
Boyd, D ;
Schierle, C ;
Beckwith, J .
PROTEIN SCIENCE, 1998, 7 (01) :201-205
[6]   Assessing sequence comparison methods with reliable structurally identified distant evolutionary relationships [J].
Brenner, SE ;
Chothia, C ;
Hubbard, TJP .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (11) :6073-6078
[7]   GENE DUPLICATIONS IN HAEMOPHILUS-INFLUENZAE [J].
BRENNER, SE ;
HUBBARD, T ;
MURZIN, A ;
CHOTHIA, C .
NATURE, 1995, 378 (6553) :140-140
[8]   The PRESAGE database for structural genomics [J].
Brenner, SE ;
Barken, D ;
Levitt, M .
NUCLEIC ACIDS RESEARCH, 1999, 27 (01) :251-253
[9]   PROTEINS - 1000 FAMILIES FOR THE MOLECULAR BIOLOGIST [J].
CHOTHIA, C .
NATURE, 1992, 357 (6379) :543-544
[10]   Protein folds in the all-beta and all-alpha classes [J].
Chothia, C ;
Hubbard, T ;
Brenner, S ;
Barns, H ;
Murzin, A .
ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE, 1997, 26 :597-627
123456