Phaeohyphomycosis caused by Medicopsis romeroi in solid organ transplant recipients: Report of two cases and comprehensive review of the literature

被引:9
作者
Los-Arcos, Ibai [1 ,2 ]
Royuela, Meritxell [3 ]
Teresa Martin-Gomez, M. [4 ]
Alastruey-Izquierdo, Ana [5 ]
Sellares, Joana [6 ]
Perello, Manel [6 ]
Castells, Lluis [7 ]
Dopazo, Cristina [8 ]
Gavalda, Joan [1 ,2 ]
Len, Oscar [1 ,2 ]
机构
[1] Hosp Univ Vall dHebron, Infect Dis Dept, Barcelona, Spain
[2] Univ Autonoma Barcelona, Dept Med, Barcelona, Spain
[3] ALTHAIA Xarxa Assistencial Univ Manresa, Dept Internal Med, Manresa, Spain
[4] Hosp Univ Vall dHebron, Dept Microbiol, Barcelona, Spain
[5] Inst Salud Carlos III, Natl Ctr Microbiol, Mycol Reference Lab, Madrid, Spain
[6] Hosp Univ Vall dHebron, Dept Nephrol, Barcelona, Spain
[7] Univ Autonoma Barcelona, CIBERehd, Dept Internal Med, Liver Unit,Hosp Univ Vall dHebron, Barcelona, Spain
[8] Hosp Univ Vall dHebron, Dept HPB Surg & Transplants, Barcelona, Spain
关键词
dematiaceous fungi; melanized fungi; posaconazole; solid organ transplantation; voriconazole; PYRENOCHAETA-ROMEROI; FUNGAL-INFECTIONS;
D O I
10.1111/tid.13072
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Medicopsis romeroi is a melanized coelomycetous fungus, mainly found in tropical and subtropical regions and an uncommon cause of infection in solid organ transplant (SOT) recipients. We describe two cases of SOT recipients diagnosed with phaeohyphomycosis due to M romeroi and provide a comprehensive literature review. These infections should be considered in patients native to tropical countries with a localized skin and soft tissue infection. Sequencing is needed for accurate identification of uncommon melanized fungi. Surgical treatment is recommended to cure the infection and co-adjunctive oral antifungals should be considered.
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页数:6
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