Melanin Transfer: The Keratinocytes Are More than Gluttons

被引:39
作者
Delevoye, Cedric [1 ,2 ]
机构
[1] Inst Curie, Ctr Rech, Paris, France
[2] CNRS, UMR144, Paris, France
关键词
MELANOSOME TRANSFER; PIGMENTATION; TRAFFICKING; MECHANISM; CELLS;
D O I
10.1038/jid.2013.487
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Skin pigmentation is tightly linked to the transfer of melanin from melanocytes to neighboring keratinocytes. For decades, cellular mechanisms underlying pigment transfer have remained enigmatic. Tarafder et al. identify a keratinocyte-initiated process coupling the exocytosis and endocytosis of melanin as a major pigment transfer mode in epidermis. These findings open new paths in our understanding of melanocyte-keratinocyte communication regulating pigmentation.
引用
收藏
页码:877 / 879
页数:3
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