Melanin Transfer: The Keratinocytes Are More than Gluttons

被引：39

作者：

Delevoye, Cedric ^{[1
,2
]}

机构：

[1] Inst Curie, Ctr Rech, Paris, France

[2] CNRS, UMR144, Paris, France

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2014年 / 134卷 / 04期

关键词：

MELANOSOME TRANSFER; PIGMENTATION; TRAFFICKING; MECHANISM; CELLS;

D O I：

10.1038/jid.2013.487

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Skin pigmentation is tightly linked to the transfer of melanin from melanocytes to neighboring keratinocytes. For decades, cellular mechanisms underlying pigment transfer have remained enigmatic. Tarafder et al. identify a keratinocyte-initiated process coupling the exocytosis and endocytosis of melanin as a major pigment transfer mode in epidermis. These findings open new paths in our understanding of melanocyte-keratinocyte communication regulating pigmentation.

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收藏

页码：877 / 879

页数：3

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