Enantio selective addition of alkynes to imines in ionic liquids

被引：35

作者：

Rosa, JN

Santos, AG

Afonso, CAM ^{[1
]}

机构：

[1] Inst Super Tecn, CQFM, Dept Engn Quim, P-1049001 Lisbon, Portugal

[2] Univ Nova Lisboa, Fac Ciencias & Tecnol, Dept Quim, REQUIMTE,CQFB, P-2829516 Caparica, Portugal

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2004年 / 214卷 / 01期

关键词：

ionic liquids; reuse; recycling; enantioselective catalysis; imines; propargylamines;

D O I：

10.1016/j.molcata.2003.10.065

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The enantioselective alkyne-imine addition catalysed by copper(I)-bis(oxazoline) (box) can be efficiently performed in the ionic liquid 1-n-butyl-3-methyl imidazolium bis(trifluoromethylsulfonyl)imide [bmim][NTf2]. Several substrates were tested and the reuse of the catalytic CuOTf/(box) was carried out for six cycles allowing high overall yield (87%) and enantioselectivity (first cycle 94%, sixth cycle 89%). (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：161 / 165

页数：5