The role of the mLDL-induced activation of the complement system classical pathway and C3 expression stimulation in atherosclerosis
被引:2
作者:
Drapkina, O. M.
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机构:
Sechenov Univ, IM Sechenov Moscow State Med Univ 1, Minist Hlth Russia, Moscow, RussiaSechenov Univ, IM Sechenov Moscow State Med Univ 1, Minist Hlth Russia, Moscow, Russia
Drapkina, O. M.
[1
]
Gegenava, B. B.
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机构:
Sechenov Univ, IM Sechenov Moscow State Med Univ 1, Minist Hlth Russia, Moscow, RussiaSechenov Univ, IM Sechenov Moscow State Med Univ 1, Minist Hlth Russia, Moscow, Russia
Gegenava, B. B.
[1
]
Fomin, V. V.
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机构:
Sechenov Univ, IM Sechenov Moscow State Med Univ 1, Minist Hlth Russia, Moscow, RussiaSechenov Univ, IM Sechenov Moscow State Med Univ 1, Minist Hlth Russia, Moscow, Russia
Fomin, V. V.
[1
]
机构:
[1] Sechenov Univ, IM Sechenov Moscow State Med Univ 1, Minist Hlth Russia, Moscow, Russia
complement;
modified LDL;
the classical pathway;
the C3 gene expression;
LOW-DENSITY-LIPOPROTEIN;
LIVER X RECEPTOR;
C1;
COMPLEX;
INNATE;
IMMUNE;
CHOLESTEROL;
RECOGNITION;
IMMUNOLOGY;
MECHANISMS;
PATHOGENESIS;
D O I:
10.26442/terarkh2018904100-104
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
The role of modified low density lipoprotein in the activation of the classical pathway of the complement system and increasing expression C3 gene in human macrophages is described, role of these processes on the progression of atherosclerotic vascular lesions is considering.
机构:
Inst Biol Struct Jean Pierre Ebel, Lab Enzymol Mol, 41 Rue Jules Horowitz, F-38027 Grenoble 1, FranceInst Biol Struct Jean Pierre Ebel, Lab Enzymol Mol, 41 Rue Jules Horowitz, F-38027 Grenoble 1, France
Arlaud, Gerard J.
Biro, Adrienn
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机构:
Inst Biol Struct Jean Pierre Ebel, Lab Enzymol Mol, 41 Rue Jules Horowitz, F-38027 Grenoble 1, FranceInst Biol Struct Jean Pierre Ebel, Lab Enzymol Mol, 41 Rue Jules Horowitz, F-38027 Grenoble 1, France
Biro, Adrienn
Ling, Wai Li
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机构:
Inst Biol Struct Jean Pierre Ebel, Lab Microscopie Elect Struct, F-38027 Grenoble 1, FranceInst Biol Struct Jean Pierre Ebel, Lab Enzymol Mol, 41 Rue Jules Horowitz, F-38027 Grenoble 1, France
机构:
Inst Biol Struct Jean Pierre Ebel, Lab Enzymol Mol, 41 Rue Jules Horowitz, F-38027 Grenoble 1, FranceInst Biol Struct Jean Pierre Ebel, Lab Enzymol Mol, 41 Rue Jules Horowitz, F-38027 Grenoble 1, France
Arlaud, Gerard J.
Biro, Adrienn
论文数: 0引用数: 0
h-index: 0
机构:
Inst Biol Struct Jean Pierre Ebel, Lab Enzymol Mol, 41 Rue Jules Horowitz, F-38027 Grenoble 1, FranceInst Biol Struct Jean Pierre Ebel, Lab Enzymol Mol, 41 Rue Jules Horowitz, F-38027 Grenoble 1, France
Biro, Adrienn
Ling, Wai Li
论文数: 0引用数: 0
h-index: 0
机构:
Inst Biol Struct Jean Pierre Ebel, Lab Microscopie Elect Struct, F-38027 Grenoble 1, FranceInst Biol Struct Jean Pierre Ebel, Lab Enzymol Mol, 41 Rue Jules Horowitz, F-38027 Grenoble 1, France