The role of the mLDL-induced activation of the complement system classical pathway and C3 expression stimulation in atherosclerosis

被引:2
作者
Drapkina, O. M. [1 ]
Gegenava, B. B. [1 ]
Fomin, V. V. [1 ]
机构
[1] Sechenov Univ, IM Sechenov Moscow State Med Univ 1, Minist Hlth Russia, Moscow, Russia
关键词
complement; modified LDL; the classical pathway; the C3 gene expression; LOW-DENSITY-LIPOPROTEIN; LIVER X RECEPTOR; C1; COMPLEX; INNATE; IMMUNE; CHOLESTEROL; RECOGNITION; IMMUNOLOGY; MECHANISMS; PATHOGENESIS;
D O I
10.26442/terarkh2018904100-104
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The role of modified low density lipoprotein in the activation of the classical pathway of the complement system and increasing expression C3 gene in human macrophages is described, role of these processes on the progression of atherosclerotic vascular lesions is considering.
引用
收藏
页码:100 / 104
页数:5
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