The confirmation of volatiles by solid-phase microextraction and GC-MS in the investigation of two traffic fatalities

被引:22
作者
Brewer, WE [1 ]
Galipo, RC [1 ]
Morgan, SL [1 ]
Habben, KH [1 ]
机构
[1] UNIV S CAROLINA,DEPT CHEM & BIOCHEM,COLUMBIA,SC 29208
关键词
D O I
10.1093/jat/21.4.286
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A simple, sensitive, and reliable method was developed for the confirmation of nonroutine volatiles in the investigation of two traffic fatalities. Solid-phase microextraction (SPME) fibers were used to extract volatile compounds from the headspace of sample vials; components were subsequently analyzed by gas chromatrography-mass spectrometry (GC-MS). In the first case, ethanol and methylene chloride were detected in a urine sample by headspace SPME and GC-MS. The second case involved the analysis of volatile petroleum products from submitted specimens by headspace SPME and GC-MS. In both cases, SPME and GC-MS analyses provided crucial evidence in the investigation of the traffic fatalities.
引用
收藏
页码:286 / 290
页数:5
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