PIP-DB: the Protein Isoelectric Point database

被引：22

作者：

Bunkute, Egle ^{[1
]}

Cummins, Christopher ^{[2
]}

Crofts, Fraser J. ^{[1
]}

Bunce, Gareth ^{[1
]}

Nabney, Ian T. ^{[2
]}

Flower, Darren R. ^{[1
]}

机构：

[1] Aston Univ, Sch Life & Hlth Sci, Birmingham B4 7ET, W Midlands, England

[2] Aston Univ, Sch Engn & Appl Sci, Birmingham B4 7ET, W Midlands, England

来源：

BIOINFORMATICS | 2015年 / 31卷 / 02期

关键词：

WEB-ACCESSIBLE DATABASE; MOLECULAR-WEIGHTS; PK(A) VALUES; CAPILLARY; ELECTROPHORESIS; IDENTIFICATION; PEPTIDE; JENPEP; TABLE;

D O I：

10.1093/bioinformatics/btu637

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A protein's isoelectric point or pI corresponds to the solution pH at which its net surface charge is zero. Since the early days of solution biochemistry, the pI has been recorded and reported, and thus literature reports of pI abound. The Protein Isoelectric Point database (PIP-DB) has collected and collated these data to provide an increasingly comprehensive database for comparison and benchmarking purposes. A web application has been developed to warehouse this database and provide public access to this unique resource. PIP-DB is a web-enabled SQL database with an HTML GUI front-end. PIP-DB is fully searchable across a range of properties.

引用

页码：295 / 296

页数：2

共 24 条

[1] Database resources of the National Center for Biotechnology Information [J].

Acland, Abigail ;

Agarwala, Richa ;

Barrett, Tanya ;

Beck, Jeff ;

Benson, Dennis A. ;

Bollin, Colleen ;

Bolton, Evan ;

Bryant, Stephen H. ;

Canese, Kathi ;

Church, Deanna M. ;

Clark, Karen ;

DiCuccio, Michael ;

Dondoshansky, Ilya ;

Federhen, Scott ;

Feolo, Michael ;

Geer, Lewis Y. ;

Gorelenkov, Viatcheslav ;

Hoeppner, Marilu ;

Johnson, Mark ;

Kelly, Christopher ;

Khotomlianski, Viatcheslav ;

Kimchi, Avi ;

Kimelman, Michael ;

Kitts, Paul ;

Krasnov, Sergey ;

Kuznetsov, Anatoliy ;

Landsman, David ;

Lipman, David J. ;

Lu, Zhiyong ;

Madden, Thomas L. ;

Madej, Tom ;

Maglott, Donna R. ;

Marchler-Bauer, Aron ;

Karsch-Mizrachi, Ilene ;

Murphy, Terence ;

Ostell, James ;

O'Sullivan, Christopher ;

Panchenko, Anna ;

Phan, Lon ;

Pruitt, Don Preussm Kim D. ;

Rubinstein, Wendy ;

Sayers, Eric W. ;

Schneider, Valerie ;

Schuler, Gregory D. ;

Sequeira, Edwin ;

Sherry, Stephen T. ;

Shumway, Martin ;

Sirotkin, Karl ;

Siyan, Karanjit ;

Slotta, Douglas .

NUCLEIC ACIDS RESEARCH, 2014, 42 (D1) :D7-D17

[2] BASIC LOCAL ALIGNMENT SEARCH TOOL [J].

ALTSCHUL, SF ;

GISH, W ;

MILLER, W ;

MYERS, EW ;

LIPMAN, DJ .

JOURNAL OF MOLECULAR BIOLOGY, 1990, 215 (03) :403-410

[3] AntigenDB: an immunoinformatics database of pathogen antigens [J].

Ansari, Hifzur Rahman ;

Flower, Darren R. ;

Raghava, G. P. S. .

NUCLEIC ACIDS RESEARCH, 2010, 38 :D847-D853

[4] Activities at the Universal Protein Resource (UniProt) [J].

Apweiler, Rolf ;

Bateman, Alex ;

Martin, Maria Jesus ;

O'Donovan, Claire ;

Magrane, Michele ;

Alam-Faruque, Yasmin ;

Alpi, Emanuele ;

Antunes, Ricardo ;

Arganiska, Joanna ;

Casanova, Elisabet Barrera ;

Bely, Benoit ;

Bingley, Mark ;

Bonilla, Carlos ;

Britto, Ramona ;

Bursteinas, Borisas ;

Chan, Wei Mun ;

Chavali, Gayatri ;

Cibrian-Uhalte, Elena ;

Da Silva, Alan ;

De Giorgi, Maurizio ;

Dogan, Tunca ;

Fazzini, Francesco ;

Gane, Paul ;

Castro, Leyla Garcia ;

Garmiri, Penelope ;

Hatton-Ellis, Emma ;

Hieta, Reija ;

Huntley, Rachael ;

Legge, Duncan ;

Liu, Wudong ;

Luo, Jie ;

MacDougall, Alistair ;

Mutowo, Prudence ;

Nightingale, Andrew ;

Orchard, Sandra ;

Pichler, Klemens ;

Poggioli, Diego ;

Pundir, Sangya ;

Pureza, Luis ;

Qi, Guoying ;

Rosanoff, Steven ;

Saidi, Rabie ;

Sawford, Tony ;

Shypitsyna, Aleksandra ;

Turner, Edward ;

Volynkin, Vladimir ;

Wardell, Tony ;

Watkins, Xavier ;

Zellner, Hermann ;

Corbett, Matt .

NUCLEIC ACIDS RESEARCH, 2014, 42 (D1) :D191-D198

[5] JenPep: a database of quantitative functional peptide data for immunology [J].

Blythe, MJ ;

Doytchinova, IA ;

Flower, DR .

BIOINFORMATICS, 2002, 18 (03) :434-439

[6] Gel based isoelectric focusing of peptides and the utility of isoelectric point in protein identification [J].

Cargile, BJ ;

Bundy, JL ;

Freeman, TW ;

Stephenson, JL .

JOURNAL OF PROTEOME RESEARCH, 2004, 3 (01) :112-119

[7] The NCBI Taxonomy database [J].

Federhen, Scott .

NUCLEIC ACIDS RESEARCH, 2012, 40 (D1) :D136-D143

[8] CALCULATION OF THE ISOELECTRIC POINTS OF NATIVE PROTEINS WITH SPREADING OF PK(A) VALUES [J].

HENRIKSSON, G ;

ENGLUND, AK ;

JOHANSSON, G ;

LUNDAHL, P .

ELECTROPHORESIS, 1995, 16 (08) :1377-1380

[9] Observed peptide pI and retention time shifts as a result of post-translational modifications in multidimensional separations using narrow-range IPG-IEF [J].

Lengqvist, Johan ;

Eriksson, Hanna ;

Gry, Marcus ;

Uhlen, Kristina ;

Bjorklund, Christina ;

Bjellqvist, Bengt ;

Jakobsson, Per-Johan ;

Lehtio, Janne .

AMINO ACIDS, 2011, 40 (02) :697-711

[10] Isoelectric Point, Electric Charge, and Nomenclature of the Acid-Base Residues of Proteins [J].

Maldonado, Andres A. ;

Ribeiro, Joao M. ;

Sillero, Antonio .

BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION, 2010, 38 (04) :230-237

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