Preparation of new chlorambucil analogs by bis-SRN1 methodology

被引：5
作者：
Benakli, K [1 ]
Terme, T [1 ]
Vanelle, P [1 ]
机构：
[1] Fac Pharm Marseille, Chim Organ Lab, CNRS, UMR 6517, F-13385 Marseille 5, France
来源：
SYNTHETIC COMMUNICATIONS | 2002年 / 32卷 / 12期
关键词：
D O I：
10.1081/SCC-120004080
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Three series of chlorambucil analogs were prepared by an original reaction of 1-(3-chloro-2-chloromethylpropenyl)-4-nitrobenzene with various nitronate anions under electron transfer reaction conditions.
引用
收藏
页码：1859 / 1865
页数：7
相关论文
共 12 条
  • [1] BANK BB, 1989, CANCER RES, V49, P554
  • [2] CHESON BD, 1993, SCI ADV CLIN DEV
  • [3] CHRONIC LYMPHOCYTIC-LEUKEMIA - AN UPDATED REVIEW
    FAGUET, GB
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 1994, 12 (09) : 1974 - 1990
  • [4] PERACID OXIDATION OF ALIPHATIC-AMINES - GENERAL SYNTHESIS OF NITROALKANES
    GILBERT, KE
    BORDEN, WT
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1979, 44 (04) : 659 - 661
  • [5] Cross-linking of human placenta pi class glutathione S-transferase dimer by chlorambucil
    Hathout, Y
    Ellis, T
    Fabris, D
    Fenselau, C
    [J]. CHEMICAL RESEARCH IN TOXICOLOGY, 1996, 9 (06) : 1044 - 1049
  • [6] PREPARATION OF 2-SUBSTITUTED AND 5-SUBSTITUTED-1,3-DIOXANES
    LINDEN, GB
    GOLD, MH
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1956, 21 (10) : 1175 - 1176
  • [7] INFLUENCE OF CHLORAMBUCIL, A BIFUNCTIONAL ALKYLATING AGENT, ON THE HISTONE VARIANT BIOSYNTHESIS OF HEP-2 CELLS
    SOURLINGAS, TG
    ALEPOROUMARINOU, V
    PATARYAS, TA
    SEKERIPATARYAS, KE
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1991, 1092 (03) : 298 - 303
  • [8] Sourlingas TG, 1997, BIOCHEM MOL BIOL INT, V42, P1103
  • [9] PREPARATION AND ANTIPARASITIC ACTIVITY OF NEW IMIDAZOLES BEARING DIOXANE OR HEXAHYDROPYRIMIDINE MOIETY
    VANELLE, P
    MALDONADO, J
    CROZET, MP
    SENOUKI, K
    DELMAS, F
    GASQUET, M
    TIMONDAVID, P
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1991, 26 (07) : 709 - 714
  • [10] Cascade S(RN)1 reactions in 5-nitroimidazole series
    Vanelle, P
    Benakli, K
    Maldonado, J
    Roubaud, C
    Crozet, M
    [J]. HETEROCYCLES, 1996, 43 (04) : 731 - 735
12