Regulatory functions of γδ T cells

被引：57

作者：

Peters, Christian ^{[1
]}

Kabelitz, Dieter ^{[1
]}

Wesch, Daniela ^{[1
]}

机构：

[1] Christian Albrechts Univ Kiel, Inst Immunol, Arnold Heller Str 3,Haus 17, D-24105 Kiel, Germany

来源：

CELLULAR AND MOLECULAR LIFE SCIENCES | 2018年 / 75卷 / 12期

关键词：

Suppressive; Gammadelta; T Lymphocytes; FoxP3; Adenosine; Checkpoint; TGF-beta; IL-10; TGF-BETA; ORAL TOLERANCE; MESSENGER-RNA; TUMOR-CELLS; TOLL-LIKE; SUPPRESSION; EXPRESSION; RECEPTOR; DIFFERENTIATION; INDUCTION;

D O I：

10.1007/s00018-018-2788-x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

gamma delta T cells share characteristics of innate and adaptive immune cells and are involved in a broad spectrum of pro-inflammatory functions. Nonetheless, there is accumulating evidence that gamma delta T cells also exhibit regulatory functions. In this review, we describe the different phenotypes of regulatory gamma delta T cells in correlation with the identified mechanisms of suppression.

引用

页码：2125 / 2135

页数：11

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