Exercise Pathophysiology in Interstitial Lung Disease

被引：27

作者：

Molgat-Seon, Yannick ^{[1
,2
]}

Schaeffer, Michele R. ^{[1
,2
]}

Ryerson, Christopher J. ^{[1
,3
]}

Guenette, Jordan A. ^{[1
,2
,3
]}

机构：

[1] St Pauls Hosp, Ctr Heart Lung Innovat, 166-1081 Burrard St, Vancouver, BC V6T 1Y6, Canada

[2] Univ British Columbia, Fac Med, Dept Phys Therapy, 212 Friedman Bldg,2177 Wesbrook Mall, Vancouver, BC V6T 1Z3, Canada

[3] Univ British Columbia, Fac Med, Div Resp Med, Gordon & Leslie Diamond Hlth Care Ctr, 7th Floor,2775 Laurel St, Vancouver, BC V5Z 1M9, Canada

来源：

CLINICS IN CHEST MEDICINE | 2019年 / 40卷 / 02期

基金：

加拿大健康研究院;

关键词：

Dyspnea; Exercise intolerance; Hypoxemia; Idiopathic pulmonary fibrosis; Pulmonary gas exchange; Restrictive ventilatory impairment; IDIOPATHIC PULMONARY-FIBROSIS; GAS-EXCHANGE; QUADRICEPS WEAKNESS; PHYSICAL-ACTIVITY; DAILY-LIFE; HYPERTENSION; VOLUME; MECHANISMS; LIMITATION; CAPACITY;

D O I：

10.1016/j.ccm.2019.02.011

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Interstitial lung disease (ILD) is a heterogeneous group of disorders that primarily affect the lung parenchyma. Patients with ILD have reduced lung volumes, impaired pulmonary gas exchange, and decreased cardiovascular function. These pathologic features of ILD become exacerbated during physical exertion, leading to exercise intolerance and abnormally high levels of exertional dyspnea. In this review, the authors summarize the primary pathophysiologic features of patients with ILD and their effect on the integrative response to exercise.

引用

页码：405 / +

页数：18

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