An Overview on the Recent Advances in the Treatment of Infected Wounds: Antibacterial Wound Dressings

被引:70
作者
Mirhaj, Marjan [1 ]
Labbaf, Sheyda [1 ]
Tavakoli, Mohamadreza [1 ]
Seifalian, Amelia [2 ]
机构
[1] Isfahan Univ Technol, Dept Mat Engn, Esfahan 8415683111, Iran
[2] Imperial Coll London, Dept Surg & Canc, London SW7 2BX, England
关键词
antibacterial; antibiotic; infection; nanomaterial; wound dressing; wound healing; CHLORIDE (DACC)-COATED DRESSINGS; IN-VITRO; TETRACYCLINE HYDROCHLORIDE; SILVER NANOPARTICLES; NANOCOMPOSITE HYDROGEL; ANTIMICROBIAL ACTIVITY; COMPOSITE NANOFIBERS; CONTROLLED-RELEASE; HEALING PROPERTIES; ZNO NANOCOMPOSITE;
D O I
10.1002/mabi.202200014
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A wound can be surgical cuts from an operation or due to accident and trauma. The infected wound, as a result of bacteria growth within the damaged skin, interrupts the natural wound healing process and significantly impacts the quality of life. Wound dressing is an important segment of the skincare industry with its economic burden estimated at $ 20.4 billion (in 2021) in the global market. The results of recent clinical trials suggest that the use of modern dressings can be the easiest, most accessible, and most cost-effective way to treat chronic wounds and, hence, holds significant promise. With the sheer number of dressings in the market, the selection of correct dressing is confusing for clinicians and healthcare workers. The aim of this research is to review widely used types of antibacterial wound dressings, as well as emerging products, for their efficiency and mode of action. In this review, introducing antibiotics and antibacterial nanoparticles as two important and clinically widely used categories of antibacterial agents is focused. The perspectives and challenges for paving the way for future research in this field are also discussed.
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页数:19
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